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Molecularly imprinted polymers (MIPs) have aroused focus in medicinal chemistry in recent decades, especially for biomedical applications. Considering the exceptional abilities to immobilize any guest of medical interest (antibodies, enzymes, etc.), MIPs is attractive to substantial research efforts in complementing the quest of biomimetic recognition systems. This study aims to review the key-concepts of molecular imprinting, particularly emphasizes on the conformational adaptability of MIPs beyond the usual description of molecular recognition. The optimal morphological integrity was also outlined in this review to acknowledge the successful sensing activities by MIPs.

This review highlighted the fundamental mechanisms and underlying challenges of MIPs from the preparation stage to sensor applications. The progress of electrochemical and optical sensing using molecularly imprinted assays has also been furnished, with the evolvement of molecular imprinting as a research hotspot.

The lack of standard synthesis protocol has brought about an intriguing open question in the selection of building blocks that are biocompatible to the imprint species of medical interest. Thus, in this paper, the shortcomings associated with the applications of MIPs in electrochemical and optical sensing were addressed using the existing literature besides pointing out possible solutions. Future perspectives in the vast development of MIPs also been postulated in this paper.

The present review intends to furnish the underlying mechanisms of MIPs in biomedical diagnostics, with the aim in electrochemical and optical sensing while hypothesizing on future possibilities.

Electrospinning is a versatile technique for producing polymeric nanofibers by the application of electrostatic forces. The electrospinnability of polymeric solutions and the properties of electrospun nanofibers can be influenced and tuned by the process parameters. This paper aims to investigatethe influence of three key process parameters on the tensile strength of electrospun gelatin nanofibrous scaffold.

The experiments were conducted with a custom-built electrospinning system. Design of experiments of the three operating variables, namely, gelatin concentration, applied potential and feed rate, with five levels were investigated. Optimization of the tensile strength of electrospun gelatin scaffold was achieved with the aid of response surface methodology.

The resulting second-order mathematical models capable of demonstrating good correlation on the effects of the three identified process parameters with the experimental measured tensile strength, where the highest tensile strength was obtained on gelatin nanofibrous scaffold electrospun at 16per cent (w/v) gelatin concentration in acetic acid, 19 kV applied potential and 0.31 ml/h feed rate.

The resulting second-order mathematical models capable of demonstrating good correlation on the effects of the three identified process parameters with the experimental measured tensile strength, where the highest tensile strength was obtained on gelatin nanofibrous scaffold electrospun at 16per cent (w/v) gelatin concentration in acetic acid, 19 kV applied potential and 0.31 ml/h feed rate.

This study examines how unilateral supplier transaction-specific investments (TSIs), directly and indirectly, influence international buyer opportunism and the extent to which detailed contracts enable suppliers to safeguard against international buyer opportunism. The study also examines whether relationship length affects the efficacy of detailed contracts in cross-border outsourcing relationships.

The hypotheses are tested by using data collected from multiple informants working for 229 manufacturing suppliers in China. Multiple regression with a three-way interaction is used to test the hypotheses.

Unilateral supplier TSIs encourage international buyer opportunism through increased supplier dependence. Contract specificity negatively moderates the effect of supplier dependence on international buyer opportunism. This moderating effect is stronger in long-term cross-border buyer–supplier relationships than in short-term ones.

The current study extends the cross-border outsourcing literature by examining how emerging-market suppliers in a weak power position can proactively safeguard against international buyer opportunism by using detailed contracts. Our findings show that supplier dependence mediates the relationship between unilateral supplier TSIs and international buyer opportunism; detailed contracts, however, can help dependent suppliers safeguard against international buyer opportunism. In particular, the findings highlight the importance of long-term buyer–supplier relationships that enhance the efficacy of detailed contracts.

Emerging states confront staggering shortages in adequate housing stock. In response, governments have sought various supply-based solutions to mitigate growing housing deficits. While many of these mass housing efforts have not produced the desired outcome, the Republic of Korea’s Two Million Housing Drive (TMHD) was a comparatively successful intervention with its implementation from 1988 to 1992. The five-year initiative exceeded its objective with the construction of over 2.1 million units – of which two-thirds were built by the private sector. The purpose of this study is to analyse Korea’s relatively effective supply-based affordable housing approach and then extrapolate best practices and lessons learned with applications for real estate markets in the developing world. Comparative understanding of the TMHD can help promote greater access to adequate housing in the developing world, especially for the many who continue to live in impoverished conditions.

The research uses content-based and quantitative methods to analyze the case of the TMHD in Korea toward informing improvements in corresponding supply-based housing policies and programs in developing states.

While there were challenges with the TMHD, the program repositioned Korea’s urban housing market with greater access to affordable housing in cities for the lower-income and vulnerable. The TMHD enabled the subsequent effectiveness of demand-based housing policies.

There are research limitations in fully understanding the complex relationships between mass housing programs, economic growth and government policies. The abductive reasoning used in this case study enables in-depth analysis of the TMHD with generalizable inferences for middle-range theories with applications for emerging markets.

The experience of the TMHD can promote policy harmonization by helping optimize corresponding mass housing efforts in the developing world with the potential to similarly close quantitative housing deficits and expand access to adequate housing for lower-income and vulnerable households.

Deeper understanding of the TMHD can lead to reforms of other mass housing initiatives in emerging markets to make adequate housing more accessible and economical for the benefit of underserved segments of society.

The Korean experience with the TMHD can inform the optimization of other similar large-scale policies and programs seeking to sustainably overcome shortfalls in adequate housing that have become all too common in the developing world.

Incipient detection of pavement deterioration (such as crack identification) is critical to optimizing road maintenance because it enables preventative steps to be implemented to mitigate damage and possible failure. Traditional visual inspection has been largely superseded by semi-automatic/automatic procedures given significant advancements in image processing. Therefore, there is a need to develop automated tools to detect and classify cracks.

The literature review is employed to evaluate existing attempts to use Hough transform algorithm and highlight issues that should be improved. Then, developing a simple low-cost crack detection method based on the Hough transform algorithm for pavement crack detection and classification.

Analysis results reveal that model accuracy reaches 92.14% for vertical cracks, 93.03% for diagonal cracks and 95.61% for horizontal cracks. The time lapse for detecting the crack type for one image is circa 0.98 s for vertical cracks, 0.79 s for horizontal cracks and 0.83 s for diagonal cracks. Ensuing discourse serves to illustrate the inherent potential of a simple low-cost image processing method in automated pavement crack detection. Moreover, this method provides direct guidance for long-term pavement optimal maintenance decisions.

The outcome of this research can help highway agencies to detect and classify cracks accurately for a very long highway without a need for manual inspection, which can significantly minimize cost.

Hough transform algorithm was tested in terms of detect and classify a large dataset of highway images, and the accuracy reaches 92.14%, which can be considered as a very accurate percentage regarding automated cracks and distresses classification.

This study aims to investigate Feng Shui elements that can influence housing selection and property pricing in the Malaysian housing market.

A structured questionnaire encompassing 26 Feng Shui elements, which were shortlisted based on relevant previous studies, was distributed to prospective homebuyers in the Klang Valley region. The elements were inferred and ranked according to frequency, significance and importance scores. Kruskal–Wallis ANOVA tests were used to assess the ratings provided by the different respondent groups, while Spearman's rank correlation tests were utilised to measure the degree of agreement or disagreement among each pair of the ethnic group.

The results obtained indicate the following as the five most influential elements: orientation, main entrance, street location, house number and living room. Despite a multiethnic and multicultural society in Malaysia, Spearman's rank correlation tests showed that there are no differences in the prioritisation of Feng Shui elements between three distinct ethnic groups (Malay, Chinese and Indian). However, the distribution scores are statistically different between the groups. Comparing income level with Feng Shui inclinations, the three most frequently considered elements across the three income groups consistently include orientation, main entrance and street location.

The findings of this study are expected to provide guidance to property stakeholders (developers, real estate agencies, architects, local authorities) in their future development projects. For homebuyers, this study serves as a property Feng Shui checklist for home selection and investment.

This study explored the association of Feng Shui principles to housing selection and property pricing based on cultural and income factors. These findings provide useful insights for designing and positioning of residential properties in both primary and secondary housing markets in Malaysia and beyond.

Scholars and practitioners have recognized the significance of integrating environmental practices into project context. This paper focuses on project environmental practices (PEP) and identifies PEP from the life cycle perspective, which includes green design, green procurement, green construction and investment recovery. The purpose of this paper is to empirically investigate the relationship among the four aspects of PEP and their effects on environmental performance and organizational performance.

A theoretical model was established and several hypotheses were developed. This study applied a survey method to test the hypothesized relationships. Based on a sample of 159 respondents, partial least squares structural equation modeling analyses were conducted.

The results show that green design has a positive impact on green procurement, green construction and investment recovery. Green procurement is also confirmed to positively influence green construction. Further, green construction and investment recovery have a direct and positive impact on environmental and organizational performance, whereas green design and green procurement influence environmental and organizational performance indirectly through green construction. Environmental performance has a significant impact on organizational performance.

This study enhances the understanding on PEP by revealing the inter-relationships among its four aspects and establishes the links between PEP and performance outcomes. The findings will contribute to the literature on the integration of environmental principles and project context.

As the number of social media users continues to rise globally, a heated debate emerges on whether social media use improves or harms mental health, as well as the bidirectional relation between social media use and mental health. Motivated by this, the authors’ study adopts the stressor–strain–outcome model and social compensation hypothesis to disentangle the effect mechanism between social media use and psychological well-being. The purpose of this paper is to address this issue.

To empirically validate the proposed research model, a large-scale two-year longitudinal questionnaire survey on social media use was administered to a valid sample of 6,093 respondents recruited from a university in China. Structural equation modeling was employed for data analysis.

A longitudinal analysis reveals that social media use positively (negatively) impacts psychological well-being through the mediator of nomophobia (perceived social support) in a short period. However, social media use triggers more psychological unease, as well as more life satisfaction from a longitudinal perspective.

This study addresses the bidirectional relation between social media use and psychological unease. The current study also draws both theoretical and practical implications by unmasking the bright–dark duality of social media use on psychological well-being.

The paper aims to highlight the role of Web 2.0 in international marketing, shedding light on the relationships existing between the country of origin effect and consumer behavior.

The current study, drawn on the country of the origin (COO)W literature and Web 2.0 diffusion data, investigates the relationships between country of origin – seen as an idiosyncratic entrepreneurial offer – and the consumer, within an international marketing framework. Specifically, the paper focuses on the increasing role of Web 2.0 and social media as tools enabling enterprises to create and maintain adaptive and networking capabilities and to implement international marketing strategies.

The findings presented here reveal that international marketing is becoming increasingly similar to domestic marketing because of social media development. In other words, it is becoming more and more difficult for international products to contain themselves within single markets as local issues seldom remain local.

This paper fills a gap in the international marketing literature focusing on how social media, particularly in a pandemic era, can improve and enhance relationships between the product of origin and consumer behavior both in the assessment and in the actual purchase of products.