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The purpose of this study is to explore how the development of digital trade can provide new development prospects to China's foreign trade under the background of the gradual expansion of China's digital economy and the further release of policy dividends.

Using the methods of literature collection and induction, combined with traditional trade theory, this paper analyzes the characteristics and challenges of digital trade under the background of the digital economy.

The findings reveal that China's digital trade development still faces some risks, such as the containment of China's core technology, digital security and unbalanced development among regions. Considering these risks, China should break through core technical problem, participate in the formulation of international rules to ensure data security, give priority to the development of service trade and improve the unbalanced development of digital trade.

By analyzing the development status and characteristics of the digital economy and digital trade, this paper summarizes the challenges and comparative advantages faced by China's digital trade, and puts forward corresponding suggestions. These suggestions will allow China to take advantage of its rapid digital economy development and occupy a leading position in global digital trade.

This paper creatively expounds on the new development direction of digital trade from the perspective of comparative advantage and risks, and provides some suggestions to expedite China's digital trade development.

Electric fields (EFs) are known to influence cell and tissue activity. This influence can be due to thermal or non-thermal effects. While the non-thermal effects are still matter of discussion, thermal effects might be detrimental for cell and tissue viability due to thermal damage, this fact being exploited by applications like hyperthermia and tissue ablation. The paper aims to discuss these issues.

In this work the authors investigate the influence of thermal damage in the consolidation of bone formation during electrostimulation (ES). The authors introduce a mathematical model describing the migration of osteoprogenitor cells, the thermal variation, the thermal damage accumulation and the formation of new bone matrix in an injury (fracture) site.

Numerical results are in agreement with experimental data and show that EFs more intense than 7.5 V/cm are detrimental for the viability of osteoprogenitor cells and the formation of new bone.

The model is suitable to conduct dosimetry studies in support of other different ES techniques aimed at improving bone and soft tissues repair.

The purpose of this paper is to verify the feasibility and evaluate the compressive properties of Ti6Al4V implants with controlled porosity via electron beam melting process. This process might be a promising method to fabricate orthopedic implants with suitable pore architecture and matched mechanical properties.

Ti6Al4V implants with controlled porosity are produced using an electron beam melting machine. A scanning electron microscope is utilized to examine the macro‐pore structures of the Ti6Al4V implants. The compressive test is performed to investigate the mechanical properties of the porous implants.

The fabricated samples show a fully interconnected open‐pore network. The compressive yield strength of the Ti6Al4V implants with the porosity of around 51 percent is higher than that of human cortical bone. The Young's modulus of the implants is similar to that of cortical bone.

The surface of samples produced by electron beam melting process is covered with loosely spherical metal particles. Polishing and ultrasonic cleaning have to be used to remove the loose remnants.

This paper presents the potential application in the fabrication of orthopedic or dental implants using electron beam melting process.

Rapid prototyping (RP) technology is widely used in many fields in recent years. Bone tissue engineering (TE) is an interdisciplinary field involving life sciences, engineering and materials science. Hydroxyapatite (HAp) are similar to natural bone and it has been extensively studied due to its excellent biocompatibility and osteoconductivity. This paper aims to review nanoscaled HAp-based scaffolds with high porosity fabricated by various RP methods for bone regeneration.

The review focused on the fabrication methods of HAp composite scaffolds through RP techniques. The paper summarized the evaluation of these scaffolds on the basis of their biocompatibility and biodegradability through in vitro and in vivo tests. Finally, a summary and perspectives on this active area of research are provided.

HAp composite scaffold fabricated by RP methods has been widely used in bone TE and it has been deeply studied by researchers during the past two decades. However, its brittleness and difficulty in processing have largely limited its wide application in TE. Therefore, the formability of HAp combined with biocompatible organic materials and fabrication techniques could be effectively enhanced, and it can be used in bone TE applications finally.

This review paper presented a comprehensive study of the various types of HAp composite scaffold fabricated by RP technologies and introduced their potential application in bone TE, as well as future roadmap and perspective.

The purpose of this study is to obtain an effective implant with porous structures on its surface, named porous-surfaced implant, which helps to improve the overall stability of the implant and promote the combination of implant and alveolar bone.

Porous-surfaced implants with a porosity of 16%, 21%and 32% were designed and the effect of porosity on the strength of the implant was analyzed by ABAQUS software. Porous-surfaced implants with different porosity were printed by selective laser melting and the surface morphology was observed. Animal experiments of implants with porous structures and coating were carried out in healthy beagle dogs. The experimental group was treated with hydroxyapatite coating and the control group was not treated. Bone volume (BV) and total volume (TV) of the implant surface of the experimental group and control group were calculated by Skyscan CTvol software.

With the increase of porosity of porous-surfaced implants, the neck stress of the porous-surfaced implants increased and their strength decreased. In addition, in animal vivo experiments, the ratio value of BV to TV of the porous-surfaced implants was between 55.38% and 79.86%, which was the largest when the porosity of porous-surfaced implants was 16%. The internal and surrounding bone formation content of porous-surfaced implants with hydroxyapatite coating was higher than porous-surfaced implants without coating.

The results of this study show that the pores on the surface of implants can be filled with the new bone and porous-surfaced implants with 16% porosity provide better space for the growth of new bone. The porous structures with hydroxyapatite coating are beneficial to the growth of new bone around implants. The results of this study are helpful to improve the overall stability of implants and to promote the combination of implant and alveolar bone.

The purpose of this paper is to study the use of the additive manufacturing (AM) method, electron beam melting (EBM), for manufacturing of customized hip stems. The aim is to investigate EBM's feasibility and commercial potential in comparison with conventional machining, and to map out advantages and drawbacks of using EBM in this application. One part of the study concerns the influence on the fatigue properties of the material, when using the raw surface directly from the EBM machine, in parts of the implant.

The research is based on a case study of manufacturing a batch of seven individually adapted hip stems. The stems were manufactured both with conventional machining and with EBM technology and the methods were compared according to the costs of materials, time for file preparation and manufacturing. In order to enhance bone ingrowths in the medial part of the stem, the raw surface from EBM manufacturing is used in that area and initial fatigue studies were performed, to get indications on how this surface influences the fatigue properties.

The cost reduction due to using EBM in this study was 35 per cent. Fatigue tests comparing milled test bars with raw surfaced bars indicate a reduction of the fatigue limit by using the coarse surface.

The paper presents a detailed comparison of EBM and conventional machining, not seen in earlier research. The fatigue tests of raw EBM‐surfaces are interesting since the raw surface has shown to enhance bone ingrowths and therefore is suitable to use in some medical applications.

This paper aims to introduce selective vacuum manufacturing (SVM), a powder-based rapid prototyping (RP) technique, and the ongoing development to improve its capability to apply in temporary scaffold fabrication.

SVM employs a combination of sand casting and powder sintering process to construct a prototype layer by layer. A dense layer of support material is prepared and selectively removed to create a cavity where part material is filled and sintered to form a solid layer. In order for SVM to be considered for scaffold fabrication, besides preparing poly-lactic acid (PLA) for part material, support material preparation and process parameters identification have been studied. Redesigning of SVM machine to be more suitable for the real usage has also been presented.

Particle size of salt has been controlled, and its suitable composition with flour and water has been determined. Process parameters have been identified to scale down the size of scaffolds to meso-scale and to achieve mechanical requirement. Properties of fabricated scaffolds have been enhanced and can be used for soft tissue applications. A prototype of the medical SVM machine has been constructed and tested. An examination of scaffolds fabricated on this new machine also showed their qualification for soft tissue application.

Further study will be on conducting a direct cytotoxicity test to provide the evidence for tissue growth before the clinical usage, on continuing to scaling down the scaffold size, and on improving SVM to meet the requirement of hard tissue.

This simple, inexpensive RP technique demonstrates its viability for scaffold fabrication.

The requirements of open cell porous regular interconnected metallic structure (OCPRIMS) in applications such as heat exchangers, sound absorption, fluid flow control, spark arresters and biocompatible inserts have been increased. As per available technology in the present scenario, only the metallic-based rapid prototyping (RP) machines can guarantee fabrication of OCPRIMS. Metal-based RP machines are capital-intensive. So, this study aims to develop a technique for fabrication of OCPRIMS economically using three-dimensional printing (3 DP) and pressureless sintering.

Three computer-aided design (CAD) models of varying designed interconnected porosity 73, 70 and 60 per cent were modeled to target metallic porosity 27, 30 and 40 per cent. The same were fabricated with ceramic-based powder using 3 DP. Thereafter, spherical bronze powder with average size of 200 µm was filled and sintered in pressureless manner under inert atmosphere of argon. After sintering, the specimens were cleaned with the help of pricking needles and high-pressure water. It flushed the burnt ceramic powder and allowed metallic portion to remain intact. The obtained specimens were inverse of CAD/3 DP models. The dimensional measurement at different stages of fabrication was carried out to find shrinkage. Sintered density and interconnected porosity were measured using Archimedes’ principle. The characterization of the fabricated specimens was done with the help of microstructure analysis, scanning electron microscopy and energy dispersive x-ray analysis. Mechanical properties were assessed using compressive, tensile and Charpy tests.

The feasibility has been explored successfully to fabricate OCPRIMS of phosphor bronze using 3 DP and pressureless sintering process. Interconnected porosity of 51.45, 56.45, 64.09 per cent of final metallic specimens has been observed against the targeted 27, 30 and 40 per cent. The increase in pore dimensions up to 19.13 per cent and shrinkage up to 5.44 per cent of outer dimensions were found to be the main causes of increase in interconnected porosity level. The characterization results exhibit the behavior of pressureless sintering process and stability of the fabricated specimens. Mechanical properties of fabricated structures are found to be dependent on porosity and strut diameter. Compressive and tensile strength decrease with the increase in porosity for strut diameter less than 1 mm, whereas they increase with the increase in strut diameter of 1 mm or more. A similar trend has been observed for impact strength also.

This paper explores the feasibility to fabricate OCPRIMS economically using 3 DP and pressureless sintering process.

The purpose of this paper is to propose a new aerodynamic parameter estimation methodology based on neural network and output error method, while the output error method is improved based on particle swarm algorithm.

Firstly, the algorithm approximates the dynamic characteristics of aircraft based on feedforward neural network. Neural network is trained by extreme learning machine, and the trained network can predict the aircraft response at (k + 1)th instant given the measured flight data at kth instant. Secondly, particle swarm optimization is used to enhance the convergence of Levenberg–Marquardt (LM) algorithm, and the improved LM method is used to substitute for the Gauss Newton algorithm in output error method. Finally, the trained neural network is combined with the improved output error method to estimate aerodynamic derivatives.

Neither depending on the initial guess of the parameters to be estimated nor requiring numerical integration of the aircraft motion equation, the proposed algorithm can be used for unstable aircraft and is successfully applied to extract aerodynamic derivatives from both simulated and real flight data.

The proposed method requires iterative calculation and can only identify parameters offline.

The proposed method is successfully applied to estimate aircraft aerodynamic parameters and can also be used as a new algorithm for other optimization problems.

In this study, the output error method is improved to reduce the dependence on the initial value of parameters and expand its application scope. It is applied in aircraft aerodynamic parameter identification together with neural network.

We present an overview of research on spillover effects within firms and introduce a classification of the literature. We divide spillovers into either technological or social in nature. In our classification, a technological spillover is one in which an agent rationally responds to a cue in the workplace that does not rely on the identity or characteristics of a coworker. Social spillovers, on the other hand, may be thought of as arising from the social preferences of an individual or social norms established in the organization.