Alessio Pricci and Gianluca Percoco
This study aims to describe the effect of ironing process parameters on mixing efficiency and gradient generation in Y-micromixers and microfluidic gradient generators (MGGs)…
Abstract
Purpose
This study aims to describe the effect of ironing process parameters on mixing efficiency and gradient generation in Y-micromixers and microfluidic gradient generators (MGGs), respectively.
Design/methodology/approach
Material extrusion (MEX) enables the production of miniaturized devices with the advantage of lower manufacturing costs and higher design freedom. However, surface finishing is the most important drawback when it comes to microfluidic applications where flow splitting is not required. First, the effect of ironing line spacing (LS) and speed (IS) on mixing efficiency in Y-micromixers was experimentally investigated. Then, the best ironing settings were chosen to further study the spatial stability of the normalized concentration gradient in MGGs.
Findings
Lower ironing LS and IS enhance the microchannel surface smoothness. The best combination of ironing parameters (lowest values of LS and IS) leads to an increase in mixing length of 191% at Q = 10 µL/min and 198% at Q = 20 µL/min, with respect to a similar Y-micromixer geometry where ironing was not performed. These findings were applied in the production of a MGG, showing that the normalized concentration gradient in the crosswise flow direction does not depend on the streamwise position when ironing is performed.
Originality/value
To the best of the authors’ knowledge, for the first time, the possibility of optimizing ironing parameters to enhance the surface roughness in MEX microfluidic devices has been investigated. Ironing of the channel bottom surface allows to reduce ridges-induced flow convection, thus delaying mixing in Y-micromixers and achieving stable concentration gradient in MGGs.
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Mojtaba Zeraatkar, Marco Donato de Tullio, Alessio Pricci, Francesco Pignatelli and Gianluca Percoco
The purpose of this study is to introduce an alternative construction for microfluidic micromixers, where the effect of the extruded filaments in the fused deposition modeling…
Abstract
Purpose
The purpose of this study is to introduce an alternative construction for microfluidic micromixers, where the effect of the extruded filaments in the fused deposition modeling (FDM) technique is used to enhance mixing performance identified as a challenge in microfluidic micromixers.
Design/methodology/approach
A simple Y-shaped micromixer was designed and printed using FDM technique. Experimental and numerical studies were conducted to investigate the effect of the extruded filaments on the flow behavior. The effects of the extruded width (LW), distance between adjacent filaments (b) and filament height (h1) are investigated on the mixing performance and enhancing mixing in the fabricated devices. The performance of fabricated devices in mixing two solutions was tested at flow rates of 5, 10, 20, 40, 80 and 150 µL/min.
Findings
The experimental results showed that the presence of geometrical features on microchannels, because of the nature of the FDM process, can act as ridges and generate a lateral transform through the transverse movement of fluids along the groove. The results showed the effect of increasing ridge height on the transverse movement of the fluids and, therefore, chaotic mixing over the ridges. In contrast, in the shallow ridge, diffusion is the only mechanism for mixing, which confirms the numerical results.
Originality/value
The study presents an exciting aspect of FDM for fabrication of micromixers and enhance mixing process. In comparison to other methods, no complexity was added in fabrication process and the ridges are an inherent property of the FDM process.