Search results

The purpose of this study was to develop the modified risk calculator for the Pakistani population based on differences in perceived versus actual risk factors for developing type 2 diabetes mellitus (T2-DM).

A cross-sectional study design was developed to assess the study sample of 296 individuals from the Pakistani population. The data was collected using a questionnaire divided into three parts: general health, the validated Risk Perception Survey for Developing Diabetes (RPS-DD) and actual T2-DM risk assessment.

The study findings showed that among the total participants, 70.27% reported a low perceived risk of developing T2-DM, whereas 29.72% reported a high perceived risk when considering their family history. Regarding actual risk, males showed a 59% higher likelihood of developing T2-DM than females, who have a 50% higher risk. The modified calculator includes physical activity, fatty food consumption, age 34–65 and over 65, depression and artificially sweetened beverages.

This study experienced limited representativeness; many participants provided incomplete nutritional and knowledge information. It involved 296 individuals, mostly from one province and a few from other provinces of Pakistan. Therefore, the results can be generalized to the whole Pakistani population.

This study underscores the need for targeted interventions to enhance risk perception, inform preventive strategies and further investigate the interplay between perceived and actual risks in T2-DM in Pakistan.

The outcomes of this study can help Pakistani individuals who perceive themselves at an elevated risk of developing T2-DM. There is a general awareness among the Pakistani population regarding T2-DM. In contrast to perceived risk, the data on actual risk reveals a significant disconnect.

In Pakistan, there is a lack of research on perceived versus actual risk factors for developing T2-DM. To the best of the authors’ knowledge, this is the first study that evaluates the actual risk factors of developing T2-DM based on culture and dietary diversity in Pakistan.

To evaluate the efficacy of a PRECEDE model-based educational program in enhancing awareness, attitudes and preventive behaviors against diabetes complications among rural patients with type 2 diabetes mellitus (T2DM).

This quasi-experimental study included 160 T2DM patients from rural health centers in Andimeshk, Iran (2020–2021). Participants were randomly assigned to intervention (n = 80) or control (n = 80) groups. The intervention group received a six-session in-person educational program, supplemented by weekly lifestyle videos via WhatsApp over six weeks, guided by PRECEDE model constructs. A validated questionnaire assessed knowledge, attitudes, enabling and reinforcing factors, and preventive behaviors pre- and post-intervention.

Post-intervention, the intervention group demonstrated significantly (p < 0.001) higher mean scores in knowledge, attitudes, enabling factors, reinforcing factors and preventive behaviors than controls. Fasting blood sugar (FBS) levels were significantly (p < 0.001) reduced in the intervention group at three-month follow-up.

The findings demonstrate that a comprehensive program grounded in the PRECEDE model can significantly enhance patients’ awareness, strengthen positive attitudes, increase enabling and reinforcing factors and promote preventive lifestyle behaviors. Importantly, the intervention led to improved glycemic control, as evidenced by reduced fasting blood sugar levels at three-month follow-up. These results suggest that tailored, theory-driven educational initiatives have the potential to empower rural patients with type 2 diabetes to make sustainable lifestyle changes and better manage their condition. The study provides a model for developing and implementing effective diabetes self-management programs in underserved rural communities, which can ultimately contribute to reducing diabetes-related complications and improving overall health outcomes in this population.

The purpose of this meta-analysis was to examine the effect of pomegranate juice (PJ) intake on glycemic control in adults.

Materials and methods: PubMed (Medline), ISI Web of Science, Cochrane Library and Scopus databases, measuring glucose and/or insulin and Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) in adults, were searched from inception to December 11, 2021. Moreover, to examine whether grouping factors influenced heterogeneity between research results, subgroup analysis was used.

This meta-analysis showed that PJ intake reduced HOMA-IR significantly, especially if =250 mL was used. This reducing effect remained significant in females, nondiabetic patients and unhealthy subjects.

The authors believe the presented data would be highly motivating and of a wide readership for the readers of your journal, and this paper stimulating a surge of research on the impact of PJ consumption on glycemic indices.

This study aims to present a great deal of interest in researching plant-based phytopharmaceuticals and nutraceuticals as a possible alternative to synthetic medication, both to avoid their side effects and for financial reasons.

Mankind has used medicinal plants since the beginning of civilization. Nature has been explored as a source of therapeutic chemicals for thousands of years, and many modern drugs have been discovered from natural sources. The primary medical care system of resource-poor areas in India has continued to rely on traditional medicine as the most accessible and reasonably priced form of treatment.

Tinospora cordifolia is a plant that is frequently used in Ayurvedic and traditional medicine throughout India. Although almost all of its parts are used in conventional medical systems, the leaves, stems and roots are the most significant ones used medicinally. All forms of existence can benefit from the versatility of T. cordifolia. It includes a wide variety of compounds that impact the body.

The goal of this review is to provide a concise summary of the knowledge about the pharmacological, phytochemistry, botanical, ethnopharmacology, toxicity study, marketed products and patents of the T. cordifolia plant.

In the state of Hawaii, it has been shown that certain ethnic minority groups, such as Filipinos and Pacific Islanders, suffer disproportionally high rates of cardiovascular disease, evidence that local health-care systems and governing bodies fail to equally extend the human right to health to all. This study aims to examine whether these ethnic health disparities in cardiovascular disease persist even within an already globally disadvantaged group, the houseless population of Hawaii.

A retrospective chart review of records from Hawaii Houseless Outreach and Medical Education Project clinic sites from 2016 to 2020 was performed to gather patient demographics and reported histories of type II diabetes, obesity, hyperlipidemia, hypertension and other cardiovascular disease diagnoses. Reported disease prevalence rates were compared between larger ethnic categories as well as ethnic subgroups.

Unexpectedly, the data revealed lower reported prevalence rates of most cardiometabolic diseases among the houseless compared to the general population. However, multiple ethnic health disparities were identified, including higher rates of diabetes and obesity among Native Hawaiians and other Pacific Islanders and higher rates of hypertension among Filipinos and Asians overall. The findings suggest that even within a generally disadvantaged houseless population, disparities in health outcomes persist between ethnic groups and that ethnocultural considerations are just as important in caring for this vulnerable population.

To the best of the authors’ knowledge, this is the first comprehensive study focusing on ethnic health disparities in cardiovascular disease and the structural processes that contribute to them, among a houseless population in the ethnically diverse state of Hawaii.

This study aims to comprehensively analyze the current developments and applications of paper-based electrochemical platforms for blood glucose detection, focusing on their potential to revolutionize point-of-care testing through cost-effective and accessible diagnostic solutions.

The review systematically examines fundamental principles of paper-based platforms, including substrate properties, fluid transport mechanisms and electrochemical detection methods. It critically evaluates recent technological advances in materials science, fabrication techniques and signal amplification strategies while analyzing various case studies demonstrating successful implementations.

Recent innovations in paper-based glucose sensors have achieved remarkable performance metrics, with detection limits reaching sub-millimolar ranges and response times within seconds. The integration of nanomaterials, particularly graphene-based composites and carbon nanotubes, has significantly enhanced sensor sensitivity and stability. Advanced enzyme immobilization techniques using layer-by-layer assembly have demonstrated sustained activity for up to 10 weeks, while novel signal amplification strategies incorporating bimetallic nanoparticles have pushed detection limits into the sub-picogram range.

This review uniquely synthesizes the latest developments in paper-based electrochemical glucose sensing, providing critical insights into the synergistic integration of advanced materials, fabrication methods and detection strategies. It offers valuable perspectives on overcoming current technical challenges and highlights emerging opportunities in smart device integration and artificial intelligence applications, serving as a comprehensive resource for researchers and practitioners in the field of point-of-care diagnostics.

Protein-energy wasting is a common complication among patients with kidney failure undergoing dialysis. This study aims to develop a homemade oral nutrition supplement (ONS) to fulfill the energy and protein requirements of these patients.

Three formulations of homemade ONS were developed using soybean milk, whey protein isolates and canola oil. Two of these formulations were flavored with pineapple and honeydew juices, respectively. The energy and macronutrient contents were determined using proximate analyses, and mineral contents were determined using inductively coupled plasma optical emission spectroscopy. The acceptance of homemade ONS for five attributes, namely color, taste, odor, consistency and overall acceptability, was assessed using the nine-point hedonic scale.

The homemade ONS provided 198–212 kcal and 8.4–9.6 g protein per 100 mL, which were comparable to commercial products. Similarly, the sodium (45–65 mg/100 mL) and phosphorus (56–66 mg/100 mL) contents were on par with commercial products. However, the potassium content of homemade ONS was higher, ranging from 141 to 155 mg per 100 mL. The sensory evaluation indicated that the formulation added with honeydew juice had a similar degree of acceptance as the commercial ONS, while formulations containing pineapple juice and without added fruit juice were less favored.

A few studies have investigated the development of food products for individuals with kidney failure on dialysis. However, to the best of the authors’ knowledge, this is the first study to focus on developing a homemade ONS specifically tailored to meet the unique nutritional needs of hemodialysis patients. In addition, this research included a comprehensive assessment of the beverage’s nutritional content and sensory attributes.

This study aims to identify the reasons for unmet health-care needs and related barriers among the Roma population with chronic diseases in Jordan.

A descriptive survey with a cross-sectional design was conducted, involving a sample of 347 Jordanian Roma participants. Data collection was performed using a structured questionnaire based on the Canadian Community Health Survey.

The analysis revealed that within the three categories of reasons for unmet health-care needs (accessibility, availability and acceptability), “Transportation issues” under the accessibility category constitute the most reported reasons: (mean = 90.4%, SD = 22.6%), followed by “Cost” (mean = 89.0%, SD = 26.2%) and “Care not available in the area” (mean = 85.8%, SD = 23.6%). Predictors of unmet health-care needs were being married, having health insurance and self-perception of mental health (OR = 0.215, p = 0.044), (OR = 0.391, p = 0.008) and (OR = 0.302, p = 0.002) respectively.

Unmet health-care needs are highly prevalent among Jordanian Roma, rendering them a vulnerable group susceptible to other diseases. To address this pressing issue, concerted and comprehensive efforts should be made to improve the utilization and accessibility of health-care services within this community. Furthermore, efforts should be made to elevate their social standing and status. facilitate their integration into the broader community.

This study introduces a comprehensive bibliometric analysis of the foreign direct investment (FDI) literature by multinational corporations (MNCs) focusing on emerging economies to identify the most influential authors, journals and articles in FDI research and reveals the fields' conceptual and intellectual structures. The purpose of this paper is to address these issues.

The study analyzed 533 articles published between 1974 and 2020 in 226 academic journals indexed in the Web of Science (WoS) and Scopus databases. We used the R language for statistical computing to map author collaboration, co-word and develop a conceptual and intellectual map of the field.

The results show that, although the FDI literature has many authors, few dominate the field. The International Business Review (IBR) and International Journal of Emerging Markets (IJoEM) are the main sources of the publications. Moreover, bibliometric laws show that our dataset follows the Lotka law of scientific productivity and Bradford law of scattering, identifying the core journals. Finally, FDI by MNCs in emerging economies research is divided into four sub-research themes related to (1) FDI determinants, (2) entry mode, (3) MNCs and FDI performance and (4) the internationalization process.

The current article provides several starting points for practitioners and researchers investigating FDI. It contributes to broadening the vision of the field and offers recommendations for future studies.

The purpose of this study was to determine the association between intrinsic capacity (IC) and dynapenia in older adults in outpatient clinics at the Naval Medical Center.

The study design was observational, analytical and retrospective. The study from which the collected data came was an observational analytical cohort, whose main objective was to describe the factors associated with frailty in older adults. The population comes from the Peruvian Naval Medical Center. This was a retrospective, observational, analytical study of the factors associated with frailty in older adults from the Naval Medical Center of Peru.

Data from 1667 participants was analyzed, 682 of them were female (40.9%) and 985 were male (50.1%); regarding age, most participants had 71–80 years (n = 761, 45.6%). Prevalence of the dynapenia was 34.5% (n = 576), and 80.08% (n = 1335) had an altered IC. In an adjusted model using Poisson regression, a prevalence ratio of 2.76 (95%, CI 2.06–3.70) was found. In conclusion, there is an association between IC and dynapenia in older adults.

In Latin America and Peru, there is limited information regarding this topic and tools for the evaluation of IC.