Antiproliferative activity of Bacaba (Oenocarpus bacaba ) and Jenipapo (Genipa americana L. ) phenolic extracts: A comparison of assays
Abstract
Purpose
The aim of this work is to assess antiproliferative effects of phenolic extracts from Bacaba (Oenocarpus bacaba) and Jenipapo (Genipa americana) fruits through a comparison of assays.
Design/methodology/approach
Bacaba and Jenipapo phenolic extracts in a concentration range from 0 to 1400 μg/mL were tested by four different assays (MTT, MUH, methylene blue, trypan blue) to assess the antiproliferative potential of the phenolic compounds of these fruits.
Findings
MTT test can be applied with confidence to assess antiproliferative activity to the fruits extracts here studied. The extract of Bacaba showed higher antiproliferative activity than the one of Jenipapo.
Originality/value
Getting to know biofunctional properties of locally consumed fruits such as Bacaba and Jenipapo could enhance commercial properties to these fruits. This study is the first to one to assess the antiproliferative activity of the Brazilian fruits Bacaba and Jenipapo.
Keywords
Citation
Abadio Finco, F.D.B., Böser, S. and Graeve, L. (2013), "Antiproliferative activity of Bacaba (
Publisher
:Emerald Group Publishing Limited
Copyright © 2013, Emerald Group Publishing Limited