Influence of α‐tocopherol on the levels of serum anti‐oxLDL antibodies

Abstract

Purpose

This paper aims to evaluate the association between the α‐tocopherol with the levels of serum anti‐oxLDL autoantibodies and the risk markers for cardiovascular disease.

Design/methodology/approach

A normolipidemic control group (n=30) and a hypercholesterolemic group (n=33) were used. Plasma lipid profile (colorimetric method), anti‐oxLDL autoantibodies (ELISA) and α‐tocopherol (HPLC) were analysed.

Findings

The α‐tocopherol (β=−0.714; p=0.001) is negatively associated with anti‐oxLDL autoantibodies in serum and with other risk markers for cardiovascular disease (BMI, WC, total cholesterol, LDL‐c) and positively associated with HDL‐c.

Originality/value

Oxidized low density lipoprotein (oxLDL) and their autoantibodies are increased in subjects with hypercholesterolemia. The α‐tocopherol can influence the levels of serum anti‐oxLDL autoantibodies.

Citation

Sanibal, E.A.A., Damasceno, N.R.T., Gidlund, M.A. and Torres, E.A.F.S. (2009), "Influence of α‐tocopherol on the levels of serum anti‐oxLDL antibodies", Nutrition & Food Science, Vol. 39 No. 1, pp. 50-58. https://doi.org/10.1108/00346650910930824