Libin Yang, Dong Wang, Hong Gao, Hui Cao, Yuzhen Zhao, Zongcheng Miao, Zhou Yang and Wanli He
This study aims to develop a new kind of functional low molecular weight organic dyes, which is highly efficient, meanwhile inexpensive and easily prepared and modified and can be…
Abstract
Purpose
This study aims to develop a new kind of functional low molecular weight organic dyes, which is highly efficient, meanwhile inexpensive and easily prepared and modified and can be used in photoacoustic (PA) imaging and photothermal therapy (PTT). To further realize the release of molecules under the biomedical condition, the releasing efficiency of micellar nanoparticles under different stimuli were represented.
Design/methodology/approach
A class of azo and Schiff base derivatives with different click reagents were characterized by PA imaging and photothermal (PT) experiments. The molecule with best PT effect was loaded into a temperature-stimuli-sensitive amphiphilic block copolymer which demonstrated the capability of releasing the polymers under the near-infrared (NIR) light of 650 nm.
Findings
The PA and PT effects of a series of azo and Schiff base derivatives with different click reagents were characterized. Introducing the click reagent F4-TCNQ can result in red shift of peaks of PA intensity. Stimulated with 650 nm laser irradiation, the polymer processed higher release rate than being stimulated by temperature stimuli.
Practical implications
This paper not only guides the design of NIR dyes with good PA intensity but also provides a method which has great potential for the application of NIR photothermal dyes in the field of biotechnology for controlled release.
Originality/value
This paper uses click reagents to modify azo and Schiff derivatives and an amphiphilic block copolymer under NIR light to realize controlled release.
Details
Keywords
Yuzhen Zhao, Yang Zhao, Xiaoxi Kang, Zongcheng Miao and Haiquan Zhang
This paper aims to compare the electronic properties of perylene diimide derivatives (DFPDI) and its anion radical (DFPDI.-k.+) thin film by drop-coating of organic molecules on…
Abstract
Purpose
This paper aims to compare the electronic properties of perylene diimide derivatives (DFPDI) and its anion radical (DFPDI.-k.+) thin film by drop-coating of organic molecules on the interdigitated electrodes.
Design/methodology/approach
The authors compared the electronic properties of perylene diimide derivatives and its anion radical by drop-coating of organic molecules on interdigitated electrodes. Significantly, the current of perylene diimide derivatives anion radical increased by 2∼3 orders of magnitude compared to perylene diimide derivatives under a bias of 5 V, and the maximal current of anion radical that from tetrahydrofuran solution can reach 3.6 mA. Furthermore, DFPDI.-k.+ thin film showed time-resistance sensitivity for acetic acid. When DFPDI.-k.+ thin film was placed in acetic acid of 3.1 × 105 ppm, the current was decreased 46 times under a bias of 6 V after 8 min.
Findings
We developed the new method to prepare ambient stable perylene diimide derivatives anion radical, which shows sensitivity of absorption spectra to acid.
Originality/value
Perylene diimide derivatives anion radical thin film showed time-resistance sensitivity for acetic acid, suggesting potential application of perylene diimide derivatives anion radical as acid sensor.