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Although many conventional level-set approaches can be used for segmenting images containing factors such as noise and intensity inhomogeneities, they still can impact the accuracy of the results seriously. To solve this problem, a level-set method for fast image segmentation based on pre-fitting and bilateral filtering is proposed.

Firstly, an improved bilateral filter was investigated for image preprocessing. Secondly, by computing the local average intensity of the preprocessed enhanced picture, two local pre-fitting functions were defined. Thirdly, a new level-set energy functional was defined. Finally, a new distance regularized energy term based on the logarithmic and polynomial functions is proposed to evolve the level-set function in a smooth state.

The experimental results demonstrate that the proposed model has an excellent segmentation capability for images with noise and intensity inhomogeneities and has different degrees of performance improvement compared with the mainstream models.

(C1) An improved bilateral filter was investigated and integrated into the model. (C2) Proposing two local pre-fitting functions by computing the local average intensity of the preprocessed enhanced image. (C3) Proposing a new level-set energy functional. (C4) A new distance regularized energy term based on the logarithmic and polynomial functions is proposed to evolve the level set function in a smooth state. (C5) Analyzing and comparing the performance of the proposed model with other similar models.

This study aims to summarize the critical issues in medical federated learning and applicable solutions. Also, detailed explanations of how federated learning techniques can be applied to the medical field are presented. About 80 reference studies described in the field were reviewed, and the federated learning framework currently being developed by the research team is provided. This paper will help researchers to build an actual medical federated learning environment.

Since machine learning techniques emerged, more efficient analysis was possible with a large amount of data. However, data regulations have been tightened worldwide, and the usage of centralized machine learning methods has become almost infeasible. Federated learning techniques have been introduced as a solution. Even with its powerful structural advantages, there still exist unsolved challenges in federated learning in a real medical data environment. This paper aims to summarize those by category and presents possible solutions.

This paper provides four critical categorized issues to be aware of when applying the federated learning technique to the actual medical data environment, then provides general guidelines for building a federated learning environment as a solution.

Existing studies have dealt with issues such as heterogeneity problems in the federated learning environment itself, but those were lacking on how these issues incur problems in actual working tasks. Therefore, this paper helps researchers understand the federated learning issues through examples of actual medical machine learning environments.