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Article
Publication date: 5 June 2024

Majid Amin, Fuad A. Awwad, Emad A.A. Ismail, Muhammad Ishaq, Taza Gul and Tahir Saeed Khan

(1) A mathematical model for the Hybrid nanofluids flow is used as carriers for delivering drugs. (2) The flow conditions are controlled to enable drug-loaded nanofluids to flow…

Abstract

Purpose

(1) A mathematical model for the Hybrid nanofluids flow is used as carriers for delivering drugs. (2) The flow conditions are controlled to enable drug-loaded nanofluids to flow through the smaller gap between the two tubes. (3) Hybrid nanofluids (HNFs) made from silver (Ag) and titanium dioxide (TiO2) nanoparticles are analyzed for applications of drug delivery. (Ag) and (TiO2) (NPs) are suitable candidates for cancer treatment due to their excellent biocompatibility, high photoactivity, and low toxicity. (4) The new strategy of artificial neural networks (ANN) is used which is machine-based and more prominent in validation, and comparison with other techniques.

Design/methodology/approach

The two Tubes are settled in such a manner that the gap between them is uniform. The Control Volume Finite Element Method; Rk-4 and Artificial Neural Network (ANN).

Findings

(1) From the obtained results it is observed that the dispersion and distribution of drug-loaded nanoparticles within the body will be improved by the convective motion caused by hybrid nanofluids. The effectiveness and uniformity of drug delivery to target tissues or organs is improved based on the uniform flow and uniform gap. (2) The targeting efficiency of nanofluids is further improved with the addition of the magnetic field. (3) The size of the cylinders, and flow rate, are considered uniform to optimize the drug delivery.

Research limitations/implications

(1)The flow phenomena is considered laminar, one can use the same idea through a turbulent flow case. (2) The gap is considered uniform and will be interesting if someone extends the idea as non-uniform.

Practical implications

(1) To deliver drugs to the targeted area, a suitable mathematical model is required. (2) The analysis of hybrid nanofluids (HNFs) derived from silver (Ag) and titanium dioxide (TiO2) nanoparticles is conducted for the purpose of drug delivery. The biocompatibility, high photoactivity, and low toxicity of (Ag) and (TiO2) (NPs) make them ideal candidates for cancer treatment. (3) Machine-based artificial neural networks (ANN) have a new strategy that is more prominent in validation compared to other techniques.

Social implications

The drug delivery model is a useful strategy for new researchers. (1) They can extend this idea using a non-uniform gap. (2) The flow is considered uniform, the new researchers can extend the idea using a turbulent case. (3) Other hybrid nanofluids flow, in the same model for other industrial usages are possible.

Originality/value

All the obtained results are new. The experimental thermophysical results are used from the existing literature and references are provided.

Details

Multidiscipline Modeling in Materials and Structures, vol. 20 no. 4
Type: Research Article
ISSN: 1573-6105

Keywords

Article
Publication date: 15 June 2021

Taza Gul, Abdul Qadeer, Wajdi Alghamdi, Anwar Saeed, Safyan Mukhtar and Muhammad Jawad

This paper aims to consider the heat transportation together with irreversibility analysis for the flow of couple stress hybrid nanofluid past over a stretching surface. The…

Abstract

Purpose

This paper aims to consider the heat transportation together with irreversibility analysis for the flow of couple stress hybrid nanofluid past over a stretching surface. The innovative characteristics of this paper include electro-magnetohydrodynamic (EMHD) term, viscous dissipation, Joule heating and heat absorption\omission. The hybrid nanofluid is prepared due to the suspension of the solid nanoparticles of the single wall and multi-wall carbon nanotubes (SWCNTs and MWCNTs) in the blood for the testing purpose of heat transfer and drug deliveries. The experimental value of the Prandtl number used for the blood is 21 from the available literature and very large as compared to the Prandtl number of the other base fluids. Appropriate transformations are incorporated to convert the modeled partial differential equations into the nonlinear ordinary differential equations. The homotopy analysis method (HAM) is used to obtain the solution. The explanation for velocity, energy and entropy are exposed under the influence of various parameters such as E, M, k, Q, S and Ec. The numerical values are calculated and summarized for dimensionless Cf and Nu.

Design/methodology/approach

In this investigation, heat transportation together with irreversibility analysis for the flow of couple stress hybrid nanofluid past over a stretching surface is considered. The innovative characteristics of this paper include EMHD term, viscous dissipation, Joule heating and heat absorption\omission. The hybrid nanofluid is prepared due to the suspension of the solid nanoparticles of the SWCNTs and MWCNTs in the blood for the testing purpose of heat transfer and drug deliveries. The experimental value of the Prandtl number used for the blood is 21 from the available literature and very large as compared to the Prandtl number of the other base fluids. Appropriate transformations are incorporated to convert the modeled partial differential equations into the nonlinear ordinary differential equations. The HAM is used to obtain the solution. The explanation for velocity, energy and entropy are exposed under the influence of various parameters such as E, M, k, Q, S and Ec. The numerical values are calculated and summarized for dimensionless Cf and Nu.

Findings

The explanation for velocity, energy and entropy are exposed and the flow against various influential factors is discussed graphically. The numerical values are calculated and summarized for dimensionless In addition, the current study is compared for various values of to that published literature and an impressive agreement in terms of finding is reported. It has also been noticed that the and factors retards the hybrid nanofluid flow, while the temperature of fluid becomes upsurges by the rise in these factors.

Originality/value

This is examined while evaluating the previously discussed publications that study on EMHD aspects of magnetized Casson type hybrid nanofluid via entropy generation research is innovative but also acknowledging that the couple stress model challenged bilaterally on stretching surface has not yet been studied. So, there is an ongoing attempt to bridge such a space.

Details

International Journal of Numerical Methods for Heat & Fluid Flow, vol. 32 no. 2
Type: Research Article
ISSN: 0961-5539

Keywords

Abstract

Details

Journal of Intelligent Manufacturing and Special Equipment, vol. 4 no. 1
Type: Research Article
ISSN: 2633-6596

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