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The present study aims to explore the relationship between manufacturing–research and development (R&D) integration and organizational culture in enhancing quality and product development performance (PDP).

Based on data collected from 931 manufacturing firms around world, the authors examine the proposed hypothesis by using regression analyses. In addition, PROCESS (SPSS macro) is used to test both the mediation and moderated mediation models in this study.

The findings reveal that quality management practices (QMPs) partially mediate the relationship between R&D-manufacturing integration and PDP. Further, it is found that the direct and indirect effects of R&D-manufacturing integration on PDP are stronger when the organization is characterized as participative rather than hierarchical.

This study, by investigating the combined effect of R&D-manufacturing integration and organizational culture on QMPs and PDP, provides practical insights into the ways that manufacturing firms effectively utilize the integration between R&D and manufacturing functions to improve QMPs and enhance PDP.