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Discusses the advent of simultaneous engineering as the new manufacturing paradigm, and speculates about the organizational consequences of this new manufacturing method. To decrease the time from product inspection through prototype manufacture, it is necessary to instil a knowledge of process capabilities into the design process. Simultaneous engineering stresses design of product and production process together with design of assembly, quality control, and field service, that is the complete production cycle. There are many ways that a product can be designed to allow simplification of the product manufacture. This new method has necessitated new forms of internal organization of the company through blurring between different divisions of a company and the creation of multifunctional teams composed of domain experts from every stage of production. This new manufacturing mode has also redefined the relationship between the companies and their vendors. Because of greater technological interdependence, and even without any formal ties, concludes that long‐term relationships are becoming more and more important in many industries.

Gastric cancer is the fourth most common cancer and the leading cause of death after lung cancer in the world. Considering the economic burden of cancers and their impact on household welfare, this study aims to estimate the cost of gastric cancer in Tabriz (Northwest city of Iran) in 2017.

This was an incidence-based cost of illness study which was conducted from the perspective of society with a bottom-up costing approach. The inclusion criteria for the study were all patients (n = 118) with gastric cancer at the period of the first six months after diagnosis that 102 patients participated. Data were analyzed using SPSS software version 22.

The mean medical direct cost was US$3288.02, 18.19 per cent paid by the patient and 81.81 per cent paid by insurance organizations and governmental subsidies. The estimated out of pocket rate was 18.19 per cent. The mean non-medical direct cost estimated at US$377.54. The mean total direct cost was US$3665.56, 26.61 per cent paid by the patient. The mean indirect cost estimated at US$505.41 and the mean total cost was US$4170.97, 35.5 per cent which imposed on the patient. The mean total cost of gastric cancer within the first six months after diagnosis was equivalent to 0.81 GDP per capita.

Based on the findings, gastric cancer is a highly costly disease that despite insurance coverage imposes a high economic burden on the patients and their families.

The purpose of this paper is to investigate the three-dimensional natural convection and entropy generation in a cuboid enclosure filled with two immiscible fluids of nanofluid and air.

One surface of the enclosure is jagged and another one is smooth. The finite volume approach is applied for computation. There are two partially side heaters. Furthermore, the Navier–Stokes equations and entropy generation formulation are solved in the 3D form.

The effects of different governing parameters, such as the jagged surface (JR=0, 0.02, 0.04, 0.08, 0.12 and 0.16), Rayleigh number (10³⩽Ra⩽10⁶) and solid volume fraction of nanofluid (φ=1, 1.5, 2 vol%), on the fluid flow, temperature field, Nusselt number, volumetric entropy generation and Bejan number are presented, comprehensively. The results indicate that the average Nusselt number increases with the increase in the Rayleigh number and solid volume fraction of nanofluid. Moreover, the flow structure is significantly affected by the jagged surface.

The originality of this work is to analyze the natural-convection fluid flow and heat transfer under the influence of jagged surfaces of electrodes in high-current lead–acid batteries.