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The imperative to conserve resources and minimize operational expenses has spurred a notable increase in the adoption of lean manufacturing within the context of the circular economy across diverse industries in recent years. However, a notable gap exists in the research landscape, particularly concerning the implementation of lean practices within the pharmaceutical industry to enhance circular economy performance. Addressing this void, this study endeavors to identify and prioritize the pivotal drivers influencing lean manufacturing within the pharmaceutical sector.

The outcome of this rigorous examination highlights that “Continuous Monitoring Process for Sustainable Lean Implementation,” “Management Involvement for Sustainable Implementation” and “Training and Education” emerge as the most consequential drivers. These factors are deemed crucial for augmenting circular economy performance, underscoring the significance of management engagement, training initiatives and a continuous monitoring process in fostering a closed-loop practice within the pharmaceutical industry.

The findings contribute valuable insights for decision-makers aiming to adopt lean practices within a circular economy framework. Specifically, by streamlining the process of developing a robust action plan tailored to the unique needs of the pharmaceutical sector, our study provides actionable guidance for enhancing overall sustainability in the manufacturing processes.

This study represents one of the initial efforts to systematically identify and assess the drivers to LM implementation within the pharmaceutical industry, contributing to the emerging body of knowledge in this area.

Since Industry 4.0 (I4.0) is a new idea in Bangladesh, this study supports I4.0 adoption. Companies struggle to implement I4.0 and fully profit from the fourth industrial revolution’s digital transformation due to its novelty. Although barriers to I4.0 adoption are thoroughly studied, the literature has hardly examined the many aspects that are crucial for I4.0 adoption in Bangladesh’s Ready-Made Garment (RMG) industry. So, the purpose of this study is to investigate the barriers of adopting I4.0 in relation to Bangladesh’s RMG industries to enhance the adoption of I4.0 by developing a framework. Ultimately, the goal of this research is to improve the adoption of I4.0 in Bangladesh.

Through a comprehensive analysis of the existing research, this paper aims to reveal the barriers that must be overcome for I4.0 to be adopted. For evaluating those barriers, a decision analysis framework based on the combination of Delphi technique and Decision-Making Trial and Evaluation Laboratory (DEMATEL) method has been developed. The use of DEMATEL has led to a ranking model of those barriers and a map of how the barriers are connected to each other.

The findings reveal that “I4.0 training”, “Lack of Motivation” and “Resistance to Change” are the most significant barriers for adopting Industry 4.0 in RMG sector of Bangladesh based on their prominence scores.

These findings will help the people who make decisions in the RMG industry of Bangladesh, such as company owners, managers and the executive body, come up with a plan for putting I4.0 practices into place successfully. The decision-making framework developed in this research can be utilized by the RMG industry of Bangladesh and other similar industries in developing countries to figure out how important each barrier is for them and how to get rid of them in order of importance.

As far as the authors are aware, there has not been a comprehensive study of the barriers inhibiting the adoption of I4.0 within the scope of Bangladeshi RMG industry. This work is the first to uncover these barriers and analyze them using the combination of Delphi technique and DEMATEL.