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This paper aims to reduce the cost of experiments required to test the efficiency of materials suitable for artificial tissue ablation by increasing efficiency and accurately forecasting heating properties.

A two-step numerical analysis is used to develop and simulate a bioheat model using improved finite element method and deep learning algorithms, systematically regulating temperature distributions within the hydrogel artificial tissue during radiofrequency ablation (RFA). The model connects supervised learning and finite element analysis data to optimize electrode configurations, ensuring precise heat application while protecting surrounding hydrogel integrity.

The model accurately predicts a range of thermal changes critical for optimizing RFA, thereby enhancing treatment precision and minimizing impact on surrounding hydrogel materials. This computational approach not only advances the understanding of thermal dynamics but also provides a robust framework for improving therapeutic outcomes.

A computational predictive bioheat model, incorporating deep learning to optimize electrode configurations and minimize collateral tissue damage, represents a pioneering approach in interventional research. This method offers efficient evaluation of thermal strategies with reduced computational overhead compared to traditional numerical methods.

Presents a framework of manufacturing competence, and tests its theoretical validity using empirical data from a large‐scale survey. Interesting findings include: the regression analysis shows that manufacturing competence is better represented when low‐priority capabilities are not explicitly considered; the manufacturing competence index appears to have more significant statistical relationships with some performance measures (such as the return on assets and return on sales) than with others – manufacturing matters, but not equally to all the financial and market performance; the concept of manufacturing competence is found to be more influential in determining the business performance in the electronics sector than in the machinery industry. Does manufacturing competence matter equally in all industries, or does it matter more in a specific industry? If so, what makes manufacturing competence so important? Advocates further study to answer these questions and to complete the theory of manufacturing competence.

The purpose of this paper is to describe the role that the University of Toronto has had in helping to establish a Regional Centre of Expertise (RCE) on Education for Sustainable Development in Toronto, Canada. The way in which the RCE initiative has helped to move forward the university's own five‐year plan will also be discussed.

The paper begins with a historical overview of the development of the Toronto RCE, acknowledging the diverse range of NGO, governmental and educational institutions that collaborate within this network. It then describes how the RCE initiative is helping to advance the objectives of the University of Toronto's own five‐year plan. Finally, the paper details how the University of Toronto has supported specific projects of the RCE, and where it hopes to help to lead the RCE into the next phase of its development.

In addition to presenting a case study of an RCE, the paper includes critical discussion of broader conceptual issues, such as how one might best interpret “interdisciplinarity” and community “outreach” in a university setting.

The UN University's RCE is, in itself, a highly original and valuable initiative. The paper describes one of these networks and its own, unique focus, while also drawing conclusions about how universities might more actively engage with community partners to advance environmental awareness.

Celebrex became the first of a new class of drugs known as COX‐2 selective non‐steroidal anti‐inflammatory drugs. It improves treatment for arthritis sufferers without compromising the protective lining of the stomach. The purpose of this paper is to illustrate how direct‐to‐consumer advertising (DTCA) of prescription medicines can be used to rebuild faith in the cyclooxygenase‐2 (COX‐2) product category.

The case is developed using published sources and no input is required from company representatives. The presentation style follows the classic comprehensive case format used in postgraduate teaching programmes.

Business executives and strategic marketing students would benefit from a discussion on how external environmental factors can suddenly impose a review of marketing strategy. The reader learns how management addresses the business dilemma using DTCA.

A blockbuster rival drug Vioxx is withdrawn due to cardiovascular (CV) health safety concerns. A resulting dominant market situation soon becomes a business dilemma. The Federal Drug Administration calls for a “black box” warning label on Celebrex, the most serious type of warning.

The implications are that having a product in a class of its own is not enough. It highlights the need to communicate to different audiences, to both the medical profession and the end‐user. Getting doctors to recommend the medicine and pulling the product through the channel by stimulating patient demand after a health scare are paramount.

This is the first pharmaceutical business case where the withdrawal of a rival product leaves the dominant competitor in a monopoly situation. Contrary to expectation, market share plummets despite the absence of competition.

There is significant amount of literature tackling different issues related to the port industry. The present chapter focuses on a single business unit of seaports aiming at the documentation of works related to container terminals.

An effort to review, collect and present the majority of the works present in the last 30 years, between 1980 and 2010, has been made in order to picture the problems dealt and methods used by the authors in the specific research field. To facilitate the reader, studies have been grouped under five categories of addressed problems (productivity and competitiveness, yard and equipment utilization, equipment scheduling, berth planning, loading/unloading) and four modelling methodologies (mathematics and operations research, management and economics, simulation, stochastic modelling).

The analysis shows that most works focus on productivity and competitiveness issues followed by yard and equipment utilisation and equipment scheduling. In reference to the methodologies used managerial and economic approaches lead, followed by mathematics and operations research.

In reference to future research, two fields have been identified where there is scope of significant contribution by the academic community: container terminal security and container terminal supply chain integration.

The present chapter provides the framework for researchers in the field of port container terminals to picture the so far works in this research area and enables the identification of gaps at both research question and methodology level for further research.

Utilizing the 1995 Adult Education Interview compiled by the National Center for Education Statistics, this study examined the determinants of training participation among adult female employees. Drawing on Sterns’s (1986) model of individual decision-making about training, we hypothesized that baby boomer cohorts of women would have higher rates of training participation than younger and older cohorts of women. This hypothesis was confirmed by results on age group variables. We also confirmed that both mandatory continuing education requirements and technological innovation in clerical occupations increased the likelihood of overall training participation among baby boomers, while only mandatory continuing education requirements significantly affected the overall training likelihoods of older and younger cohorts. Findings for disaggregated categories of training suggest that employer-support may be critical to female training participation, especially in lower wage occupations.

The purpose of this study is to test Kim et al.’s (2012) seven-dimension memorable tourism experience (MTE) scale in a new context and with a new sample. In addition, the study aims to test for causes or relationships between satisfaction, MTE dimensions, co-creative tourism experiences and memorability, as well as the mediating effect of memorability on tourists’ behavioural intention.

This study uses a cross-sectional survey design using a questionnaire to collect data. Three trained interviewers questioned international travellers in the boarding area in Olbia-Costa Smeralda Airport while they were waiting to board their flights home. The interviewers also distributed and administered the questionnaires. The questionnaire was in English. Data collection was carried out from August to October 2017.

In terms of the theoretical implications of this study, its findings result in a different MTE construct than that of Kim et al.’s (2012) study. Although they discuss seven important experiential tourism factors that are likely to affect the memorability of a person’s experience, what emerges from the present research is that satisfaction, novelty, refreshment, involvement and knowledge significantly influence the memorability of a tourist’s experience.

This study has some limitations. First, it is highly site-specific and based on a convenience sample, rendering the findings non-generalizable to either the destination under investigation or any other tourism destination. Further studies should be conducted in other Mediterranean cities to generalise the significance of these findings. Although English can be considered the primary international language, the fact that the survey has been written only in English could have excluded non-English speakers from participating in the study. In addition, the study has not considered national domestic tourists. In the future, translating the survey into different languages and interviewing domestic tourists visiting the island might be useful.

Tourism service providers could gather feedback forms from tourists to measure and improve their satisfaction. Additionally, the multiplicity of actors involved in the tourism sector should coordinate and cooperate with one another to create tourism experiences that result in high overall visitor satisfaction. Tourism service providers could also offer new and diverse encounters, for example, the chance to attend local festivals to arouse curiosity, as studies suggest that such novel activities make the experiences particularly memorable. Public officials should also focus on site rejuvenation to appeal to novelty seekers who have visited previously.

Overall, the study highlights the discrepancies in the effects of satisfaction, MTE dimensions and co-creative tourism experience on the memorability of a trip experience in relation to previous studies. The results of the analysis refute the assumption that the seven MTE dimensions are representative across a variety of destination-specific tourist experiences. Besides the identified five dimensions, opening up the discussion on other factors that might influence the memorability of tourists’ experiences presents an updated agenda.

本研究的目的是在新的环境中用新的样本测试Kim等人（2012年）的七维MTE量表。此外, 该研究旨在测试满意度、MTE 维度、共同创意的旅游体验和纪念品之间的原因或关系, 以及纪念品对游客行为意图的中介作用。

本研究采用横截面调查设计, 使用问卷收集数据。三名经过培训的采访者在奥尔比亚-科斯塔斯梅拉达机场的登机区询问等待登机回家国际旅客。面试官还负责分发和管理英文问卷。数据收集工作于2017年8月至10月进行。

就本研究的理论意义而言, 其发现得出了与Kim等人（2012年）研究不同的MTE结构。虽然他们讨论了七个重要的体验旅游因素, 可能影响一个人的体验的纪念性, 从目前的研究得到的是, 满意度, 新奇, 精力恢复, 参与和知识显著影响游客体验的纪念性。

这项研究有一些局限性。首先, 它高度基于特定的地点, 并且基于便利样本, 使得调查结果无法与此次调研的目的地或其他旅游目的地通用。未来应在其他地中海城市进行进一步的研究, 以概括这些发现的重要性。虽然英语被认为是主要的国际通用语言, 但仅以英文编写的调查问卷可能使非英语使用者无法参与研究。此外, 该研究没有考虑国内游客。未来研究可以将调查翻译成不同的语言并采访访问该岛的国内游客。

旅游服务提供者可以从游客那里收集反馈表, 以衡量和提高他们的满意度。此外, 旅游活动的多方参与者应相互协调和合作, 创造旅游体验, 使游客的总体满意度达到较高水平。研究表明, 新颖的活动可以使旅游经历特别令人难忘, 因此, 旅游服务提供者也可以提供新的和多样化的接触, 例如, 有机会参加当地节日以唤起好奇心。政府官员还应关注网站活力, 以吸引访问网站的新奇探索者。

总体而言, 该研究强调了满意度、MTE 维度和共同创意旅游体验对旅行体验的影响与之前研究相比的差异。分析结果驳斥了七个 MTE 维度在各种特定目的地的旅游体验中具有代表性的假设。除了讨论发现的五个维度外, 此研究对可能影响游客体验的可纪念性的其他因素展开了讨论, 推动并更新了现有的研究议程。

El propósito de este estudio es probar la escala MTE de Kim et al. (2012) y sus siete dimensiones, en un nuevo contexto y con una nueva muestra. Además, el objetivo del estudio es evaluar las causas o las relaciones entre, satisfacción, dimensiones MTE, experiencias co-creativas de turismo y la memorabilidad, así como el efecto mediador de la memorabilidad, en la intención de comportamiento de los turistas.

Este estudio emplea un diseño de encuesta transversal y utiliza un cuestionario para recopilar los datos. Tres entrevistadores interrogaron a viajeros internacionales en el área de embarque en el aeropuerto Olbia-Costa Smeralda, mientras esperaban en el embarque de sus vuelos de retorno. Los entrevistadores también distribuyeron y administraron los cuestionarios. El cuestionario estaba en inglés. La recolección de datos se realizó de agosto a octubre de 2017.

En términos de implicaciones teóricas del estudio, los resultados desprenden una construcción MTE diferente a la del estudio de Kim et al. (2012). Si bien, discuten los siete factores del turismo experiencial, que probablemente afecten a lo memorable de la experiencia de una persona. Lo que surge de la presente investigación es que, la satisfacción, la novedad, el refrigerio, la participación y el conocimiento influyen significativamente en en todo lo memorable de la experiencia de un turista.

Este estudio tiene algunas limitaciones. Primero, es altamente específico del sitio y se basa en una muestra de conveniencia, lo que hace que los hallazgos no sean generalizables, ni para el destino, bajo investigación, ni para ningún otro destino turístico. Se deben realizar más estudios en otras ciudades mediterráneas para poder generalizar la importancia de estos resultados. Aunque el inglés puede considerarse el principal idioma internacional, el hecho de que la encuesta se haya escrito solo en inglés podría haber excluido a los que no hablan inglés a la hora de participar en el estudio. Además, no se ha considerado a los turistas nacionales. En el futuro, podría ser útil traducir la encuesta a diferentes idiomas y entrevistar a los turistas nacionales que visitan la isla.

Los proveedores de servicios turísticos podrían recopilar formularios de comentarios de los turistas para medir y mejorar su satisfacción. Además, la multiplicidad de actores involucrados en el sector turístico debe coordinarse y cooperar entre sí para crear experiencias turísticas que resulten para una alta satisfacción de los visitantes. Los proveedores de servicios turísticos también podrían ofrecer nuevos y diversos encuentros; por ejemplo, la oportunidad de asistir a festivales locales para despertar curiosidad, ya que los estudios sugieren que actividades novedosas hacen que las experiencias sean particularmente memorables. Los funcionarios públicos también deberían centrarse en el rejuvenecimiento del sitio para atraer a los buscadores de novedades que hayan visitado anteriormente.

En general, el estudio destaca las discrepancias entre los efectos de la satisfacción, las dimensiones de MTE y la experiencia turística co-creativa en la memorabilidad de una experiencia de viaje en relación con estudios anteriores. Los resultados del análisis refutan la suposición de que las siete dimensiones MTE son representativas en una variedad de experiencias turísticas específicas del destino. Además de las cinco dimensiones identificadas, abrir la discusión sobre otros factores que podrían influir en la memorabilidad de las experiencias de los turistas presenta una agenda actualizada.

This article examines the rhetoric of recent civil service reform measures in Korea, their initial implementation, and growing concerns about their sustainability. Civil service reform in Korea was initiated by an enthusiasm for New Public Management (NPM) and public calls for reform. The changes initiated by the Korean Civil Service Commission and other government organizations have sought to encourage openness, competition, flexibility, diversity, and performance-based management. Despite the bold rhetoric heralding the reform initiatives, outcomes have fallen short of expectations, and many civil servants are losing their confidence and esprit de corps. Considering both the initial promise and the ultimate reality of Korean civil service reform, this article investigates problems and limitations confronting the sustainability of these reform measures

The purpose of this paper is to explore an identified medication error using a root cause analysis and a clinical case study.

In this paper the authors explore a medication error through the completion of a root cause analysis and case study in an aged care facility.

Research indicates that medication errors are highly prevalent in aged care and 40 per cent of nursing home patients are regularly receiving at least one potentially inappropriate medicine (Hamilton, 2009; Raban et al., 2014; Shehab et al., 2016). Insufficient patient information, delays in continuing medications, poor communication, the absence of an up-to-date medication chart and missed or significantly delayed doses are all linked to medication errors (Dwyer et al., 2014). Strategies to improve medication management across hospitalisation to medication administration include utilisation of a computerised medication prescription and management system, pharmacist review, direct communication of discharge medication documentation to community pharmacists and staff education and support (Dolanski et al., 2013).

Discussion of the factors impacting on medication errors within aged care facilities may explain why they are prevalent and serve as a basis for strategies to improve medication management and facilitate further research on this topic.