Christopher Gibbins, Margaret D. Weiss, David W. Goodman, Paul S. Hodgkins, Jeanne M. Landgraf and Stephen V. Faraone
This is the first study to evaluate ADHD-hyperactive/impulsive subtype in a large clinical sample of adults with ADHD. The Quality of Life, Effectiveness, Safety and Tolerability…
Abstract
This is the first study to evaluate ADHD-hyperactive/impulsive subtype in a large clinical sample of adults with ADHD. The Quality of Life, Effectiveness, Safety and Tolerability (QuEST) study included 725 adults who received clinician diagnoses of any ADHD sub-type. Cross-sectional baseline data from 691 patients diagnosed with the hyperactive/impulsive (HI), inattentive (IA) and combined sub-types were used to compare the groups on the clinician administered ADHD-RS, clinical features and health-related quality of life. A consistent pattern of differences was found between the ADHD-I and combined subtypes, with the combined subtype being more likely to be diagnosed in childhood, more severe symptom severity and lower HRQL. Twenty-three patients out of the total sample of 691 patients (3%) received a clinician diagnosis of ADHD -hyperactive/impulsive subtype. Review of the ratings on the ADHD-RS-IV demonstrated, however, that this group had ratings of inattention comparable to the inattentive group. There were no significant differences found between the ADHD-HI and the other subtypes in symptom severity, functioning or quality of life. The hyperactive/impulsive subtype group identified by clinicians in this study was not significantly different from the rest of the sample. By contrast, significant differences were found between the inattentive and combined types. This suggests that in adults, hyperactivity declines and inattention remains significant, making the hyperactive/impulsive sub-type as defined by childhood criteria a very rare condition and raising questions as to the validity of the HI subtype in adults.
Details
Keywords
Paul Hodgkin, Rosalind Eve, Ian Golton, James Munro and Gill Musson
This paper dicusses the experience of a team in Sheffield who have established a 3‐year programme, the FACTS project, which aims to develop a framework for changing clinical…
Abstract
This paper dicusses the experience of a team in Sheffield who have established a 3‐year programme, the FACTS project, which aims to develop a framework for changing clinical practice in primary care. The lessons learnt from the project, which involves a variety of change techniques, are described including the need to tailor programmes to local needs and cultures as well as the use of marketing as a strategy for change.
Since the 1960s, experts have predicted that we are on the verge of curing cancer. The purpose of this paper is to explore the obstacles to progress, and to propose policies that…
Abstract
Purpose
Since the 1960s, experts have predicted that we are on the verge of curing cancer. The purpose of this paper is to explore the obstacles to progress, and to propose policies that will lead more quickly to more success.
Design/methodology/approach
To speed future cures, we need to look at the traits, and methods of those innovative medical entrepreneurs who achieved breakthroughs in the past, and learn what institutions and policies enabled, or blocked, their progress.
Findings
Breakthrough innovators tend to be less-credentialed outsiders who “see what others do not see,” often by nimble and persistent pursuit of serendipitous discoveries or slow hunches. For example, Freireich and DeVita were less-credentialed outsiders. Freireich cured childhood leukemia and DeVita cured Hodgkin’s lymphoma, by pursuing nimble trial-and-error experimentation in their anti-cancer chemotherapy cocktails. Min Chiu Li pursued his slow hunch that his patients would benefit from longer chemotherapy than the mandated National Cancer Institute protocol allowed. He was fired, but his patients were cured. Today, FDA-mandated regulatory protocols, often defended as applications of the precautionary principle, greatly restrict innovative medical entrepreneurs, thereby delaying cancer cures and costing lives.
Originality/value
The paper proposes a new approach to medical innovation, allowing cancer researchers to engage in trial-and-error experiments that follow up on serendipitous discoveries and plausible hunches. The result will be more cures and longer lives.
Details
Keywords
The purpose of this paper is to discuss the human rights issues pertinent to adolescents of diverse sexual orientation and gender identities and the health consequences resulting…
Abstract
Purpose
The purpose of this paper is to discuss the human rights issues pertinent to adolescents of diverse sexual orientation and gender identities and the health consequences resulting for the transgression of these rights. In 1948, the United Nations General Assembly passed a resolution endorsing the Universal Declaration of Human Rights. Yet, 73 member states criminalize the activities of these individuals. The other member states do not impose legal penalties on these activities, yet sexual and gender minority youth within these states continue to experience acts of physical and psychological aggression.
Design/methodology/approach
A commissioned position paper grounded in a convenient scholarly literature review on this topic.
Findings
Human rights transgressions by states or individuals lead to minority stress affecting the mental health and physical health of these youth.
Originality/value
The author makes a number of recommendations to address some of the impact resulting from the transgression of human rights in the world.
Details
Keywords
Andrew J. Martin, Paul Ginns, Brad Papworth and Harry Nejad
Aboriginal students experience disproportionate academic disadvantage at school. It may be that a capacity to effectively deal with academic setback and challenge (academic…
Abstract
Purpose
Aboriginal students experience disproportionate academic disadvantage at school. It may be that a capacity to effectively deal with academic setback and challenge (academic buoyancy) can reduce the incidence of academic adversity. To the extent that this is the case, academic buoyancy may also be associated with positive educational intentions. This study explores the role of academic buoyancy in Aboriginal students’ post-school educational intentions.
Methodology/approach
The survey-based study comprises Aboriginal (N = 350) and non-Aboriginal (N = 592) high school students in Australia.
Findings
Academic buoyancy yielded larger effect sizes for Aboriginal than non-Aboriginal students’ educational intentions – particularly in senior high school when educational intentions are most likely to translate into post-school educational behaviour.
Social and practical implications
Post-school education is one pathway providing access to social opportunity. Any thorough consideration of students’ passage into and through post-school education must first consider the bases of students’ academic plans and, by implication, their decision to pursue further study. Identifying factors such as academic buoyancy in this process provides some specific direction for practice and policy aimed at optimizing Aboriginal students’ academic and non-academic development.
Originality/value of chapter
Academic buoyancy is a recently proposed construct in the psycho-educational literature and has not been investigated among Aboriginal student populations. Its role in relation to post-school educational intentions is also a novel empirical contribution for both Aboriginal and non-Aboriginal students alike.
Details
Keywords
Riya Jakhar and Surinder Singh
The escalating prevalence of non-communicable diseases has underscored the crucial role of Front-of-Pack-Labelling (FoPL) in shaping consumer decisions. However, the research in…
Abstract
Purpose
The escalating prevalence of non-communicable diseases has underscored the crucial role of Front-of-Pack-Labelling (FoPL) in shaping consumer decisions. However, the research in this field is still in its developing stage, leading to a fragmented and limited body of work. Given the critical importance of FoPL, it is imperative to conduct a comprehensive literature review of existing research to outline the academic aspect of FoPL research. This research paper aims to combine the available research to generate a systematic compilation of literature, thereby contributing to the advancement of knowledge in this vital area.
Design/methodology/approach
To achieve the objectives, a systematic literature review technique was followed. The database used for the extraction of documents was Scopus. Sixty-three articles were critically examined to extract the relevant information.
Findings
Based on the analysis types of a study conducted, data collection source, types of FoPL studied, key themes, theoretical model, antecedents, dependent/independent variables and outcome were identified. It also explained the underlying phenomenon of FoPL’s impact on the various outcomes. An integrative theoretical model was also proposed based on the underlying mechanism, antecedents, moderator, mediator and outcome. Towards the end of the paper, research gaps were also identified for future paths in unexplored areas.
Originality/value
To the best of the authors’ knowledge, this paper is the first attempt in the field of FoPL to comprehensively include all the dependent and independent variables involved and propose a framework along with future research prospects. The findings will guide researchers and policymakers.
Details
Keywords
Rosalind Eve, Ian Golton, Paul Hodgkin, James Munro and Gill Musson
There is widespread recognition that simply publishing research findings is not enough to ensure that they are carried into clinical practice. One response to this has been the…
Abstract
There is widespread recognition that simply publishing research findings is not enough to ensure that they are carried into clinical practice. One response to this has been the burgeoning “guidelines movement” of recent years, which has now reached the stage of generating guidelines for the production of guidelines. Argues that guidelines, and other forms of intervention to change clinical practice in an evidence‐based direction, will succeed only to the extent that they engage actively with the real world of clinical decision making. This world is more complex than guidelines writers acknowledge, and includes economic, administrative, professional and personal incentives as well as those provided by research evidence. Engaging with this real world may be difficult, but it opens up new possibilities for understanding how clinicians act and how evidence may be used to inform clinical practice. Such possibilities include social influences, educational outreach, providing information to patients, negotiating local coalitions on specific issues and changing the administrative environment.
Details
Keywords
The purpose of this paper is to provide a retrospection on the importance, origins and development of the research programs in the author’s career.
Abstract
Purpose
The purpose of this paper is to provide a retrospection on the importance, origins and development of the research programs in the author’s career.
Design/methodology/approach
The study uses an autobiographical approach.
Findings
Most of the articles, research monographs and books that constitute this research and publishing efforts can be categorized into seven distinct, but related, research programs: channels of distribution; marketing theory; marketing’s philosophy debates; macromarketing and ethics; relationship marketing; resource-advantage theory; and marketing management and strategy. The value system that has guided these research programs has been shaped by specific events that took place in the author’s formative years. This essay chronicles these events and the origins and development of the seven research programs.
Originality/value
Chronicling the importance, origins and development of the seven research programs will hopefully motivate and assist other scholars in developing their own research programs.