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The Iranian bio-pharma industry was the first high-tech industry in the country, which had succeeded to develop innovative products. Despite past successes, there are bottlenecks preventing the industry from meeting the national standard and plans for excellence. The purpose of this paper is to find out the challenges impeding further innovation of the firms in the industry and find solution to the issues. Based on these findings, the authors recommend a set of policies that might be of interest to the new-comer countries in biotechnology.

The institutional structure of the industry, its market situation and the players are studied using a qualitative method based on an institutional approach and an appreciative theory.

Ten challenges were found after examining the pyramid of technological capabilities. Moreover; conflicting approaches in the policies made for the national health system and industrial development are identified. Adoption of policy coherence has been highlighted as a necessary strategy to harmonize and integrate the approaches required to play a role in bio-production global market actively.

A unique focal point for the country’s strategic plans should be assigned, and the supply-side policies with demand-side policies must be balanced.

This paper is an evidence-based effort to bring policy coherence as an approach in sectoral level, while political settlement lies in governance level. The opportunities for improvement are highlighted in the Iranian bio-pharmaceutical sector, as a key technology. Moreover, the findings could be used as lessons-learned for new-comers countries.

The study aims to identify a model of commercializing entrepreneurial ideas in information and communication technology (ICT) knowledge-based companies.

A mixed method has been used in the research. The participants of the qualitative part were 15 key informants selected by sampling method purposefully and theoretically, while a sample of 205 experts was randomly chosen for the quantitative part. Data collection was completed through a semistructured interview in the qualitative part and by a researcher-made questionnaire in the quantitative part. The reliability of the research was confirmed by Cronbach’s alpha. The validity of the qualitative and quantitative parts was approved, respectively, by the criteria of Corbin and Strauss (2008) and by the content validity. Data analysis was done in the qualitative part through open, axial and selective coding, while in the quantitative part through partial least squares structural equation modeling (PLS-SEM) and adaptive neuro-fuzzy inference systems (ANFIS).

The commercialization model of ICT entrepreneurial ideas was depicted by the paradigmatic version of Corbin and Strauss (2008). The model has been consisted of six sectors as follows: causal conditions (including stimuli of science and technology parks, interests and motivation of managers of ICT knowledge-based company and environmental stimuli), contextual conditions (including skills and abilities of managers of ICT knowledge-based company, status of ICT knowledge-based company and enabling and facilitating legal framework), intervening conditions (including the complex nature of the ICT industry, science and technology parks’ support of companies, facilities and equipment for commercialization of ICT entrepreneurial ideas and economic system stability), strategies (including marketing research, planning and feasibility study of ICT entrepreneurial idea, design and production of ICT product and release and supply of ICT product), consequences (successful commercialization of ICT entrepreneurial ideas in the post-COVID-19 era) and the central phenomenon (ICT entrepreneurial ideas: commercialization in the post-COVID-19 era). Then, the main factors were confirmed through PLS-SEM and ANFIS. Among the factors, interests and motivation of managers of ICT knowledge-based companies, status of ICT knowledge-based companies, facilities and equipment for commercialization of ICT entrepreneurial ideas and release and supply of ICT products were identified as the most influential factors.

The model can help solve the challenges of managers and policymakers to commercialize ICT entrepreneurial ideas. Therefore, innovative production will increase, value will be created for the beneficiaries and economic, social and political growth will occur in the post-Corona era.

Commercialization of ICT entrepreneurial ideas has the potential to affect many aspects of economic and societal activities in the society such as GDP growth, employment, productivity, poverty alleviation, quality of life and education.

The research includes innovation in presenting a multidimensional commercialization model based on an entrepreneurial perspective in the special field of ICT with a mixed approach including grounded theory, PLS-SEM and ANFIS in ICT knowledge-based companies. But the most important innovation of the study is related to the findings. The main categories, subcategories and concepts of the research have been presented in the form of a theory entitled “ICT entrepreneurial ideas: commercialization in the post-COVID-19 era.”