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This study aimed to evaluate the compositional changes and bioaccessibility of phenolics and antioxidants in propolis during in vitro digestion as well as the cytotoxic effects of digested propolis on various cancer cell lines.

Six propolis samples were obtained and subjected to in vitro oral, gastric and intestinal digestion. Both digested and undigested samples were analyzed for their total phenolic, flavonoid and antioxidant activities. Additionally, changes in phenolic composition in the in vitro digestion system were revealed by the HPLC-DAD system. The cytotoxic effects of the digested samples were assessed on lung (A549, H1299), skin (A431), liver (Hep-G2) and colon (Caco-2) cancer cells as well as on fibroblast (Bj) cells.

The mean bioaccessibility values of phenolic and flavonoid compounds were found to be less than 35 and 24%, respectively, while the TEAC and CUPRAC antioxidant results ranged between 225.08–649.04 and 398.68–1552.28 µmol TE/g, respectively. The release of p-coumaric, ferulic, 3,4-dimethoxycinnamic acids, naringenin, pinocembrin and chrysin increased progressively from the oral to the intestinal stage. The cytotoxic effects of samples on cell lines were ranked, based on IC50 results, as A431 > Hep-G2 > Caco-2 > A549 > H1299 > Bj.

Propolis has been recognized for centuries as a natural remedy, and numerous studies have explored its bioactive components. However, no studies have previously examined the changes in the phenolic compositions of propolis samples during digestion or their cytotoxic effects on cancer cells. Therefore, this study provides novel insights and an approach to the existing literature on this topic.

The purpose of this study is to investigate the effects of consumer ethnocentrism and consumer animosity at the ethnic level. This study examines both effects on an ethnic majority’s consumption of an ethnic minority’s products and services, focusing on the relationship between two ethnic groups in Malaysia.

The relationship between the constructs were analyzed using the co-variance-based structural equation modeling techniques with analysis of a moment structures version 21. Self-administered questionnaires were obtained from 325 Malay respondents in 2 Malaysian cities.

The results suggest that ethnic-based consumer ethnocentrism can negatively affect product judgment and product judgment can affect consumers’ willingness to buy. Two significant findings were rejected as the directions of the results were not as hypothesized.

Future research could study other ethnic groups of different countries using specific ethnic related products and/or brands.

This research suggests that ethnic-based ethnocentrism and ethnic-based animosity are important factors for businesses to consider as both can affect ethnic consumers’ purchasing behavior. Depending on ethnic consumers’ perception toward a brand, a manager may face either an opportunity or a challenge.

This paper aims to identify factors that affect the sports tourism destination's competitiveness on a small island. Hence, this study looks at and evaluates these factors. The study then comes up with a model that clarifies the interrelationships between these factors.

The authors broke down the data analysis process into three steps. The first step was to conduct a literature review and use industry and academia experts' help to determine the essential aspects (fuzzy Delphi method). Then, a hierarchical model was developed, and the factors were categorised using the interpretive structural modelling (ISM) approach. Factors' driving and dependency power were also determined using MICMAC analysis.

This work has identified 13 key factors related to the sports tourism destination's competitiveness on a small island. For a small island like Kish Island, the two independent variables (government support and destination political stability) that define the institutional framework for the destination are most important. Building corresponding competitive and support strategies to address these two independent variables is thus beneficial.

The research's results provide decision-makers, practitioners, and researchers with new insights into the hierarchical model of determinants. The study will fill the existing gap between theory and practice.

Sports tourism destination managers on small islands may benefit from the proposed model since the model will enable them to organise the managers' priorities better to enhance the managers' destinations' competitiveness and provide tourists with a more accurate depiction of the destination.

According to the authors' knowledge, the research design presented in this article has provided the first attempt to hierarchical analyse these factors and develop a model for sports tourism destination competitiveness on small islands and destinations with less-developed economies. This study fills the gap in the destination competitiveness and sports tourism literature by not only identifying the key influencing factors but also examining the interactions between these factors and providing empirical evidence supporting their relationships.