Farhang Djafari, Hossein Shahinfar, Maryam Safabakhsh and Sakineh Shab-Bidar
Fruits and vegetables (FVs) are a good source of substances that contributed to bone health. However, the relation of FVs consumption with inflammation and bone biomarkers is…
Abstract
Purpose
Fruits and vegetables (FVs) are a good source of substances that contributed to bone health. However, the relation of FVs consumption with inflammation and bone biomarkers is inconsistent. Thus, this paper aims to assess the association of FVs intake with inflammation and bone biomarkers in older adults.
Design/methodology/approach
This cross-sectional study was performed on 178 older adults in Tehran, with a mean age of 67.04. Biochemical measurements including serum osteocalcin, high sensitivity c-reactive protein, 25-hydroxyvitamin D 25(OH) D, parathormone and urine terminal telopeptide of Type I collagen (u-CTx) was done. The intake of FVs was calculated using a validated quantitative food frequency questionnaire.
Findings
Pearson correlation coefficients showed a positive relation between serum osteocalcin and total vegetables (r = 0.167, p = 0.026), juices group (r = 0.155, p = 0.035), starchy vegetables (r = 0.205, p = 0.006) and other vegetable group (r = 0.161, p = 0.032) even after controlling of potential confounders. Analysis of covariance showed that total vegetable were significantly associated with serum osteocalcin (p = 0.041) and PTH levels (p = 0.028). Additionally, no evidence of a significant relationship between total fruit intake and test variables was observed. However, subgroup analyses demonstrated a significant association between citrus fruits and serum 25(OH) D (p = 0.017). A significant relation between starchy vegetable and urine CTx-I was reported (p = 0.016). Moreover, other vegetable subgroup was strongly associated with serum osteocalcin (p = 0.003).
Originality/value
The results of this paper may provide insight for clinical interventions and also important to make policy for prevention or easing bone disorders and general inflammation related to fruit and vegetable intake.
Details
Keywords
Maryam Safabakhsh, Sakineh Shab-Bidar and Hossein Imani
Recently, evidences have suggested that healthy eating index (HEI), an index-based dietary pattern, may be a predictor for the risk of cancer. This paper aims to examine the…
Abstract
Purpose
Recently, evidences have suggested that healthy eating index (HEI), an index-based dietary pattern, may be a predictor for the risk of cancer. This paper aims to examine the association of HEI-2015 and its all components scores with the risk of breast cancer (BC), separately, among Iranian women.
Design/methodology/approach
In the present hospital-based, case-control study, 150 age-matched of cases (newly diagnosed female) and 150 controls were recruited. Data of dietary habits and anthropometric measures were obtained, and eventually, the HEI-2015 score was calculated. Multivariate odds ratios (ORs) with 95% confidence intervals (CIs) were used to evaluate the relationship between the risk of BC across tertiles (Ts) of total HEI-2015 and its all component scores.
Findings
The results presented that in adjusted model, there was no significant difference between total HEI-2015 (p = 0.14) and its all component scores (p > 0.09) of healthy subjects and females with BC. Moreover, multivariable logistic regression analyses indicated that HEI-2015 score was not associated with the risk of BC in either crude (p-trend = 0.94) or adjusted (p-trend = 0.73) analyses. In the analyses of HEI-2015 components scores, it was observed that the scores of grains (OR, 0.53; 95% CI, 0.30–0.94) and total protein foods (OR, 0.13; 95% CI, 0.02–0.58) may have a relation with BC risk in crude model but after adjusting for BC risk factors, the mentioned associations changed to non-significant.
Originality/value
The findings of current study suggested that there was no significant association of total HEI-2015 and its components scores, independently, with BC incidence among Iranian women.
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Keywords
Pedram Pam, Maryam Behrooz, Mehrdad Jamali, Hosna Ghorbani, Amirataollah Hiradfar, Azim Rezamand and Zohreh Ghoreishi
The purpose of this study is to investigate the relationship between dietary total antioxidant capacity (DTAC) and the dietary inflammatory index (DII) with inflammatory status in…
Abstract
Purpose
The purpose of this study is to investigate the relationship between dietary total antioxidant capacity (DTAC) and the dietary inflammatory index (DII) with inflammatory status in children recently diagnosed with Acute Lymphoblastic Leukemia (ALL). As the relationship between diet quality scores and inflammation remains uncertain in this population, the authors carried out a hospital-based cross-sectional study.
Design/methodology/approach
The study used a cross-sectional design involving 54 children recently diagnosed with ALL. Dietary data was collected using a 147-item semi-quantitative food frequency questionnaire developed for the Tehran Lipid and Glucose Study. Inflammatory status was evaluated using various indicators like C-reactive protein (CRP), neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio (PLR), monocyte-to-lymphocyte ratio (MLR), Glasgow prognostic score (GPS) and Complete blood count-based inflammatory score.
Findings
The authors found no significant relationship between DII with inflammatory indices and length of hospitalization in patients. However, a significant inverse relationship was observed between the antioxidant indices ferric-reducing ability of plasma, total reactive antioxidant potential and Trolox equivalent antioxidant capacity with the inflammatory index MLR, respectively (ß: −0.19, p = 0.001), (ß: −0.42, p = 0.02), (ß: −0.53, p = 0.005). Also, a significant inverse relationship between FRAP and CRP was observed in the crude model (ß: −0.13, p = 0.05). FRAP was also inversely correlated with GPS and PLR, respectively (ß: −0.08, p = 0.02), (ß: −0.26, p = 0.03). No additional significant links were discovered between food scores and the outcomes studied.
Originality/value
This study found no link between DII with inflammatory markers or hospitalization duration in children with ALL. However, the authors did observe a noteworthy inverse relationship between DTAC and certain inflammatory markers like MLR. To achieve more dependable findings, further research in this area is necessary.