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Type 2 diabetes mellitus (T2DM) is a worldwide health problem. Blood pressure (BP) and inflammation are well-established risk factors for the cardiovascular complications of T2DM. Genistein is known to improve endothelial dysfunction. The purpose of this study is to investigate the effects of genistein supplementation on BP, high-sensitive C-reactive protein (hs-CRP) and homocysteine (Hcy) levels in postmenopausal women with T2DM.

This randomized, double-blind, placebo-controlled clinical trial is conducted on postmenopausal women with T2DM. A total of 54 subjects aged between 47 and 69 years are divided into two groups. Participants in the genistein group (n = 28) are given two genistein capsules (each capsule contained 54 mg genistein) and those in the placebo group (n = 26) received two placebo capsules (each capsule contained 54 mg maltodextrin) daily for 12 weeks. General characteristics, BP, hs-CRP and Hcy levels are measured at the baseline and at the end of the trial.

Genistein supplementation resulted in a significant reduction in systolic BP (SBP) (p < 0.001), diastolic BP (DBP) (p = 0.020), mean arterial pressure (MAP) (p < 0.001), serum levels of hs-CRP (p = 0.005) and Hcy (p = 0.001) in genistein group compared with placebo group at the end of the study. Significant decreases are also found in SBP by 5.4%, p < 0.001, DBP by 6.7%, p < 0.001, MAP by 6.2%, p < 0.001, serum levels of hs-CRP by 47.0%, p = 0.015 and Hcy by 18.4%, p < 0.001 in the genistein supplemented group. No significant changes are observed in terms of all post-intervention values in the placebo group.

Genistein administration improved BP, hs-CRP and Hcy levels in postmenopausal women with T2DM and may be useful in control of some CVD risk factors in these subjects.

This paper aims to study the importance of polyphenols in human health and, based on recommendations on the replacement of carbonated drinks with nutritious beverages, like fruit juices, seeks to compare the polyphenol contents of natural and commercial juices.

The total polypheol content of 39 fresh and 159 commercial (100 percent and less than 50 percent) fruit juices was analyzed by the terbium sensitized fluorescence method. The ANOVA with Tukey post hoc test, and also an independent t‐test, were used for statistical analyses.

The mean polyphenol contents of fresh juices were significantly (p<0.001) higher than those of 100 percent commercials (5.34±2.7 vs 3.28±0.86 mg/l). In fresh juices the concentration ranged from 1.06±0.08 (pineapple) to 10.14±0.07 (sour cherry) mg QE/100 ml, while in 100 percent commercial juices the range was from 2.37±0.05 (orange) to 5.34±0.4 (pomegranate) mg QE/100 ml, and in <50 percent commercial juices they ranged from 1.04±0.7 (red grape) to 2.21±0.07 (white grape) mg QE/100 ml. The polyphenol contents of dark juices, in both fresh and commercial products, were significantly higher than others (p<0.001) and most fresh fruit juices possessed higher amounts of polyphenol than commercial ones. Although various juices differed in the quantity of total polyphenol, they can be considered as a good source of functional beverage.

This paper provides information about the polyphenol content of fresh and commercial (100 percent and <50 percent) fruit juices. To the best of the authors' knowledge, there have been no articles which aim to compare the polyphenol content of Iranian fresh and commercial fruit juices. For analysing the polyphenol contents, the newly developed terbium sensitized fluorescence method was used, and also the applicability of this new method was compared with the commonly used Folin‐Ciocalteau method.

The antioxidant characteristics of fruits can be attributed to their contents of polyphenols and vitamins. Because of the interest in the role of antioxidants in human health, the purpose of this paper is to examine the major compounds associated with antioxidant activity, namely total phenolic and vitamin C contents, of some regularly cultivated and consumed fruits in Iran.

In total, 66 fruits from 22 families were chosen for this study. Terbium sensitized fluorescence assay and spectrophotometric method were used to determine total polyphenol and vitamin C contents respectively. The ANOVA with Tukey post‐hoc test was used for statistical analyses.

The total mean polyphenol content of fruits was 4.93 ± 2.86 mg QE/100 g that were ranging from 0.8 ± 0.05 to 11.94 ± 0.02 mg QE/100 g with the lowest amount obtained for pear and the highest amount detected in black grape. The polyphenol contents of black grape, sourcherry and pomegranate were significantly higher than those of other fruits (p < 0.001). The total mean vitamin C content of fresh fruits was 18.34 ± 9.77 mg/100 g that were ranging from 57.38 ± 0.02 (strawberry) to 11.44 ± 0.02 (melon) mg/100 g. The vitamin C contents of strawberry was significantly higher than all other fruits (p < 0.001). Despite the differences in the polyphenol and vitamin C contents of various fruits, as a good source of nutritious compounds and functional foods, they can be effective in enhancing health status.

This paper is believed to be the only one which provides information about the polyphenol and vitamin C contents of Iranian fruits. Also, the polyphenol content was measured by using a newly‐developed method.