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1 – 6 of 6Xudong He, GuangYi Yang, E. Yang, Moli Zhang, Dan Luo, Jingjian Liu, Chongnan Zhao, Qinhua Chen and Fengying Ran
Based on DNase I and reduced graphene oxide (rGO)-magnetic silicon microspheres (MNPS), a highly sensitive and selective fluorescent probe for the detection of PD-L1 was developed.
Abstract
Purpose
Based on DNase I and reduced graphene oxide (rGO)-magnetic silicon microspheres (MNPS), a highly sensitive and selective fluorescent probe for the detection of PD-L1 was developed.
Design/methodology/approach
Here °C we present a feasibility of biosensor to detection of PD-L1 in lung tumors plasma. In the absence of PD-L1°C the PD-L1 aptamer is absorbed on the surface of graphene oxide modified magnetic nanoparticles °8rGO-MNPS°9 and leading to effective fluorescence quenching. Upon adding PD-L1°C the aptamer sequences could be specifically recognized by PD-L1 and the aptamer/PD-L1 complex is formed°C resulting in the recovery of quenched fluorescence.
Findings
This sensor can detect PD-L1 with a linear range from 100 pg mL−1 to 100 ng mL−1, and a detection limit of 10 pg•m−1 was achieved.
Originality/value
This method provides an easy and sensitive method for the detection of PD-L1 and will be beneficial to the early diagnosis and prognosis of tumors.
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Keywords
Jiaqi Li, Guangyi Zhou, Dongfang Li, Mingyuan Zhang and Xuefeng Zhao
Recognizing every worker's working status instead of only describing the existing construction activities in static images or videos as most computer vision-based approaches do;…
Abstract
Purpose
Recognizing every worker's working status instead of only describing the existing construction activities in static images or videos as most computer vision-based approaches do; identifying workers and their activities simultaneously; establishing a connection between workers and their behaviors.
Design/methodology/approach
Taking a reinforcement processing area as a research case, a new method for recognizing each different worker's activity through the position relationship of objects detected by Faster R-CNN is proposed. Firstly, based on four workers and four kinds of high-frequency activities, a Faster R-CNN model is trained. Then, by inputting the video into the model, with the coordinate of the boxes at each moment, the status of each worker can be judged.
Findings
The Faster R-CNN detector shows a satisfying performance with an mAP of 0.9654; with the detected boxes, a connection between the workers and activities is established; Through this connection, the average accuracy of activity recognition reached 0.92; with the proposed method, the labor consumption of each worker can be viewed more intuitively on the visualization graphics.
Originality/value
With this proposed method, the visualization graphics generated will help managers to evaluate the labor consumption of each worker more intuitively. Furthermore, human resources can be allocated more efficiently according to the information obtained. It is especially suitable for some small construction scenarios, in which the recognition model can work for a long time after it is established. This is potentially beneficial for the healthy operation of the entire project, and can also have a positive indirect impact on structural health and safety.
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Fangyong Niu, Dongjiang Wu, Yunfei Huang, Shuai Yan, Guangyi Ma, Chaojiang Li and Jun Ding
Direct additive manufacturing of ceramics (DAMC) is a highly promising ceramics preparation technology because of its simple process and rapid response capability, but the…
Abstract
Purpose
Direct additive manufacturing of ceramics (DAMC) is a highly promising ceramics preparation technology because of its simple process and rapid response capability, but the cracking issue prevents its industrial application. The purpose of this paper is to propose aluminum titanate (Al2TiO5) with low coefficient of thermal expansion (CTE) to suppress cracks during the DAMC.
Design/methodology/approach
Al2O3/Al2TiO5 (A/AT) composite ceramic samples with different compositions were in-situ synthesized from Al2O3/TiO2 (A/T) powder in a directed laser deposition (DLD) process. The relationship between the content of TiO2 and cracking characteristics of fabricated sample was discussed. Phase composition, microstructure and properties of the fabricated samples were also investigated.
Findings
The results of this paper show that the doping of TiO2 can obtain Al2TiO5 synthesized in situ by reaction with Al2O3 and effectively suppress cracks during DAMC. When the content of TiO2 reaches 30 wt.per cent, cracks hardly occur even under conditions of slow deposition. Crack-free structures such as vane, cone and pyramid were successfully prepared, with a maximum cross-sectional dimension of 30 mm and maximum length of 150 mm. A continuous matrix phase formed of the low CTE of Al2TiO5 is the major cause of crack suppression. The dispersed distribution of a-Al2O3 columnar dendrites has the effect of increasing the strength of the matrix. Under current process conditions, the prepared sample with 10 wt.per cent TiO2 has micro-hardness of 21.05 GPa and flexural strength of 170 MPa.
Originality/value
This paper provides a new method and inspiration for direct additive manufacturing of large-sized crack-free ceramics, which has the potential to promote practical application of the technology.
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The purpose of this paper is to improve photoelectric detection target (PDT) optical detection performance and detection view, by analyzing its influence factors and putting…
Abstract
Purpose
The purpose of this paper is to improve photoelectric detection target (PDT) optical detection performance and detection view, by analyzing its influence factors and putting forward a new method to design its optical detection system.
Design/methodology/approach
Using rectangle linked photoelectric detector, with low noise and high response, to design optical detection system and gain faint projectile image information; bringing forward a deviating focusing technique to eliminate detection blind area of photoelectric detector; and designing adjustable slit diaphragm to weaken background light influence.
Findings
The results of experimentation in shooting range show that the new PDT has improved detection sensitivity and performance.
Originality/value
The paper presents a new design method in photoelectric detection target (PDT) optical detection system, which can provide a new method to design fire across measurement system and gain accurate projectile's coordinates data in the shooting range.
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This paper aims to investigate the effects on coatings performance in the epoxy silicone resin system owing to the existence of the different chain length of open-chain epoxy…
Abstract
Purpose
This paper aims to investigate the effects on coatings performance in the epoxy silicone resin system owing to the existence of the different chain length of open-chain epoxy monomer. In this paper, [4-Methylphenyl-(4–(2-methylpropyl) phenyl)]iodonium as photoinitiator was added into epoxy silicone resin by ultraviolet (UV)-cured polymerization to investigate the effects on coatings performance owing to the existence of the different chain length of open-chain epoxy monomer.
Design/methodology/approach
A simple hydrosilylation reaction was used to synthesize epoxy-based silicone prepolymers by using hydrogen-terminated polydimethylsiloxane, 1,2-epoxy-5-hexene, 1,2-epoxy-7-octene and 1,2-epoxy-9-decene as precursors.
Findings
The results revealed that the glass transition temperatures (Tg) and hydrophobicity increased with the chain length of open-chain epoxy monomer in the UV curable epoxy-based silicone coatings, and these films had excellent heat resistance, hydrophobicity, antigraffiti and ink removal properties.
Research limitations/implications
The cationic photocuring systems are not susceptible to the effect of oxygen inhibition. However, the limitation of cationic light curing process is that it requires a long curing time.
Originality/value
The coatings prepared via the UV curing approach can provide superior antismudge effects, and thus they are promising candidates for use in various industries, especially in fields such as antismudge coatings and antigraffiti coatings.
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Abstract
Purpose
This paper traces the incorporation of western educational histories in the development of normal-school curricula during the late Qing Dynasty and the Republic of China (1901–1944). It uses publication networks to show how the study of comparative educational history facilitated the international circulation of knowledge in the teaching profession, and how the “uses” of educational history were shaped by larger geopolitical forces.
Design/methodology/approach
This paper analyzes the international exchange of texts between normal schools in China and Japan and, subsequently, between normal schools in China and the United States. A database of 107 publications in the field of western educational history that were adopted in China reveals specific patterns of textual citation, cross-reference, and canon-formation in the field of educational historiography.
Findings
With conclusions derived from a combination of social network analysis and clustering analysis, this paper identifies three broad stages in China's development of normal-school curricula in comparative educational history: “Japan as Teacher,” “transitional period” and “America as Teacher.”
Research limitations/implications
Statistical analysis can reveal citation and reference patterns but not readers' understanding of the deeper meaning of texts – in this case, textbooks on the subject of western educational history. In addition, the types of publications analyzed in this study are relatively limited, the articles on the history of education in journals have not become the main objects of this study.
Originality/value
This paper uses both quantitative and qualitative methods to uncover the transnational circulation of knowledge in the field of comparative educational history during its formative period in China.
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