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This paper focuses on understanding the contribution of Industry 4.0 technologies to manufacturing flexibility.

A multiple-case study was conducted through interviews and complementary data from 12 adopters of Industry 4.0 technologies from the industrial sector. To enable a broad perspective, cases from 5 industry sectors with different technological intensity levels were studied.

The findings show that Industry 4.0 technologies are mostly used to improve machine flexibility since there is a major focus on technological approaches rather than on wider flexibility. The results also showed that cloud services, IoT, and data analytics provide the basis for flexible operation, and collaborative robots, ERP/MES/PLM, AGVs, and traceability devices are the most commonly implemented technologies for flexibility. However, inherent contingency factors such as production complexity and product life cycle need to be considered.

This article expands the research on manufacturing flexibility, considering new capabilities introduced by Industry 4.0.

The innovation process demands an interaction between environment agents, knowledge generators and policies of incentive for innovation and not only development by companies. Universities have gradually become the core of the knowledge production system and, therefore, their role regarding innovation has become more important and diversified. This study is aimed at identifying the mechanisms of university–industry (U–I) collaboration, as well as the operationalization steps of the U–I collaboration process.

This study is aimed at identifying, based on a systematic literature review, the mechanisms of university–industry (U–I) collaboration, as well as the operationalization steps of the U–I collaboration process.

The analysis of the 72 selected articles enabled identifying 15 mechanisms of U–I collaboration, proposing a new classification for such mechanisms and developing a framework presenting the operationalization steps of the interaction process.

In this paper, the authors screened nearly 1,500 papers and analyzed in detail 86 papers addressing U–I collaboration, mechanisms of U–I collaboration and operationalization steps of the U–I collaboration process. This paper provides a new classification for such mechanisms and developing a framework presenting the operationalization steps of the interaction process. This research contributes to both theory and practice by highlighting managerial aspects and stimulating academic research on such timely topic.