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This study aimed to evaluate the compositional changes and bioaccessibility of phenolics and antioxidants in propolis during in vitro digestion as well as the cytotoxic effects of digested propolis on various cancer cell lines.

Six propolis samples were obtained and subjected to in vitro oral, gastric and intestinal digestion. Both digested and undigested samples were analyzed for their total phenolic, flavonoid and antioxidant activities. Additionally, changes in phenolic composition in the in vitro digestion system were revealed by the HPLC-DAD system. The cytotoxic effects of the digested samples were assessed on lung (A549, H1299), skin (A431), liver (Hep-G2) and colon (Caco-2) cancer cells as well as on fibroblast (Bj) cells.

The mean bioaccessibility values of phenolic and flavonoid compounds were found to be less than 35 and 24%, respectively, while the TEAC and CUPRAC antioxidant results ranged between 225.08–649.04 and 398.68–1552.28 µmol TE/g, respectively. The release of p-coumaric, ferulic, 3,4-dimethoxycinnamic acids, naringenin, pinocembrin and chrysin increased progressively from the oral to the intestinal stage. The cytotoxic effects of samples on cell lines were ranked, based on IC50 results, as A431 > Hep-G2 > Caco-2 > A549 > H1299 > Bj.

Propolis has been recognized for centuries as a natural remedy, and numerous studies have explored its bioactive components. However, no studies have previously examined the changes in the phenolic compositions of propolis samples during digestion or their cytotoxic effects on cancer cells. Therefore, this study provides novel insights and an approach to the existing literature on this topic.

In metropolitan areas experiencing rapid urbanization and housing production, the size of housing units emerges as a crucial factor to consider in housing policy formulation. This study aims to focus on Turkey, a developing country undergoing rapid urbanization and a construction boom in recent years, to examine households’ housing size preferences. Through a detailed analysis, this research delves into the causal relationships between income, education and housing size preferences.

This study uses the Family Structure Survey in Turkey 2016 data set collected nationwide by the Turkish Statistical Institute (TurkStat). To address potential endogeneity issues related to income and education levels in households’ choice of house size, an extended regression model is used. In addition, survey weights are applied to the statistical model to generalize the results of the study.

The study demonstrates that household income correlates with an increase in house size, while household education is associated with a decrease in house size. Variables such as household age, composition and vehicle ownership are found to impact the choice of house size. Particularly, one-person and couple-only households tend to prefer smaller dwellings compared to others. Lastly, the results reveal that the influence of household composition on dwelling size varies according to household age.

This study presents a comprehensive analysis of the determinants influencing households’ housing size preferences within the framework of a developing country context, focusing on Turkey. It specifically offers insights into the causal impact of education and income levels on housing size preferences, as well as the intricate interplay between household characteristics in shaping these preferences.

This paper investigates the structural model of vector autoregression (SVAR) of the interdependent relationship of inflation, monetary policy and Islamic banking variables (RDEP, RFIN, DEP, FIN) in Indonesia. By using monthly data for the period 2001M01-2019M12, the impulse response function (IRF), forecasting error decomposition variation (FEDV) is used to track the impact of Sharīʿah variables on inflation (prices).

This research uses quantitative approach with SVAR model to reveal the problem.

The empirical results of SVAR, the IRF show that policy shocks have a negative impact on all variables in Islamic banking except the equivalent deposit interest rate (RDEP). The impact of both conventional (7DRR) and Sharīʿah (SBIS) policies has a similar pattern. While the transmission of Sharīʿah monetary variables as a policy operational target in influencing inflation is positive. In addition, the FEDV clearly revealed that the variation in the Sharīʿah financial sector was relatively large in monetary policy shocks and their role in influencing prices.

The empirical results of SVAR, the IRF show that policy shocks have a negative impact on all variables in Islamic banking except the equivalent deposit interest rate ‘RDEP’. The impact of both conventional “7DRR” and Sharīʿah “SBIS” policies has a similar pattern. While the transmission of Sharīʿah monetary variables as a policy operational target in influencing inflation is positive. In addition, the FEDV clearly revealed that the variation in the Sharīʿah financial sector was relatively large in monetary policy shocks and their role in influencing prices.