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Copy Number Variations (CNVs) are not infrequently observed in aberrant neurodevelopment. CNVs can alter gene expression and have been linked to a wide range of neuropsychiatric disorders. The purpose of this case study is to report the association of CNVs with a mixed neurodevelopmental disorder.

Array-Comparative Genomic Hybridisation analysis was carried out in a case of an eight-year-old boy presenting with a mixed neurodevelopmental disorder including autism spectrum disorder, intellectual disability, tic disorder, anxiety and severe aggression. The child's parents also underwent the same investigation.

A 6q27 deletion and multiple copies within 20q11.23 were identified. The boy's father shared the 6q27 deletion and his mother also had multiple copies within 20q11.23.

This is the first report linking the combination of 6p27 and 20q11 CNVs with a mixed neurodevelopmental presentation. Identifying CNVs that may underlie aberrant neurodevelopment is likely to assist in unravelling the aetiology of neurodevelopmental and psychiatric disorders and lead to more effective strategies for their characterisation and management.

In Nigeria, family is most important. It is usually made up of people who are related by blood, marriage, or adoption. Family plays a major role in influencing the use of psychoactive substances by adolescents and can help protect the adolescents or the reverse. Family differs in so many ways, for example, in the extent of support for education, children’s upbringing, monitoring peer activities among others. There are certain family situations where values are not being instilled, parental and social guides are not in place to ensure that children are well brought up. High levels of economic hardship (such as unemployment), family conflict, poor communication skills, domestic violence, parental divorce or single parenting, death, parental criminal activity among others disrupt parenting which reduces adolescents’ emotional security and reinforce the use of aggression and interpersonal hostility which in turn expose them to certain risks of psychoactive substance use. It is in this context that this chapter examines how family factors affect the use of psychoactive substances among adolescents in Nigeria. Empirical investigations were carried out through a review of literature search. The findings show family factors having a significant influence on the use of psychoactive substances among adolescents in Nigeria. In addition, proper parental relationship through training of moral values, teachings of the immense danger attributed to the use of psychoactive substances through counseling and communication skills could serve as a control measure that will discourage the future use and thus improve the health, safety and the general well-being of the adolescents.

The Customary Land Delivery Institutions (CLDIs) provide the platform for the supply of developable land in most cities in sub-Saharan African countries. While there is a need to measure the effectiveness of CLDIs to compare their performance with others or themselves over time, there is however a dearth of evidence-based frameworks that could be adopted for such an assessment. This study developed a framework for the evaluation of the effectiveness of CLDIs. This is with a view to providing a tool for measuring the performance of land governance.

A total of 46 good governance criteria for measuring the various dimensions of CLDIs generated from the literature were transformed into a measurable scale which was validated by a panel of 16 experts through a modified Delphi approach. A pilot study was also conducted on 42 land-based professionals to assess the reliability of the framework. Content Validity Index (CVI) was calculated for relevancy scores while clarity was measured by clarity score. Cronbach alpha was also employed to measure the reliability of the framework.

The result of the 46 criteria validated by the experts revealed that 89.5% of items in the developed instrument have a content validity index (I-CVI) equal to or greater than the 0.85 threshold and a mean I-CVI of 0.90. With the CVI score and the analysis of the comments made by the experts, six items were removed from the instrument and a total of six new items were added. The final corrected instrument after a further iteration had a total of 46 items. The reliability test also revealed a Cronbach alpha score of 0.82.

This paper provides a framework useful for developing countries, especially in the development of land delivery policies and provides a framework for the analysis of the important aspects thereof.

This paper demonstrates the development of a holistic framework for the assessment of CLDIs which hitherto were not in existence.

This paper aims to explore the use of alternative dispute resolution (ADR) techniques as a legitimate means of ejection of recalcitrant tenant in property. This is with a view of providing information that will improve property investment and management.

The paper adopts a case study approach using five selected case studies where ADR approach was used to recover premises.

The experience from the case studies shows that the use of ADR in premises recovery is effective but has its challenges. In the five case studies, consent judgment, mediation and negotiation were used to recover premises in less than three months compared to an average of 18 months using litigation. Also, the cost in all the cases were lower where they exist at all than when litigation are used. The paper provides useful information to practitioners on the use of the effective alternative approach to recover premises from recalcitrant tenants.

The paper provides practical ways through which recovery of premises could be achieved through non-adversarial technique in developing property markets, which hitherto was not available in literature.

Ọsẹ dúdú production and sale constitute a major indigenous business among the Yoruba people. Scholars have noted that the business is capable of boosting the socio-economic status of black soap entrepreneurs and of countries. However, ọsẹ dúdú enterprise has some significant threats and problems that are yet to be researched. This chapter examined the challenges of osẹ dúdú entrepreneurs in Southwest Nigeria. Twenty-six interviews were conducted among indigenous black soap producers and sellers in Ogun, Oyo and Lagos States. Data were analysed in themes. Weather, financial, spiritual, copyright and succession challenges, as well as issues such as a large number of sellers, debt, lack of support, pricing and brand competition, were found to be problems faced by black soap entrepreneurs. This chapter concluded that certain controllable and uncontrollable factors were not only capable of limiting the development of osẹ dúdú business but also have adverse implications for the achievement of the sustainable development goals through the indigenous resource. This chapter suggests that osẹ dúdú business actors such as mechanical engineers, local fabricators, financial institutions, and governmental and non-governmental agencies collaborate with black soap entrepreneurs to ameliorate the challenges of the latter. It is only through this alliance that black soap entrepreneurs can contribute to indigenous business development and the achievement of sustainable development goals in Africa.

The study had examined the dynamism in rental housing characteristic in Ile-Ife, Nigeria.

Data were collected through questionnaire administration on 550 tenants selected across high, medium and low density areas, using systematic random sampling.

Findings revealed that rented apartments in the traditional town are built with modern materials like sandcrete blocks, cement, corrugated roofing sheet and aluminium. Further findings revealed a statistical significant variation in the rental housing typologies across the residential densities (χ² = 94.732^a, df = 10 and p = 0.000). The dominant housing typology in the low income earners areas is rooming apartments known traditionally as (face-to-face), in the middle income earners areas detached and semi-detached bungalows (Mini, 2bedroms and 3 bedrooms flat); and lastly, bungalows and duplexes dominates the high income earners areas. Therefore, the study likened the variation across the income areas to deferential in socioeconomic characteristics of tenants, surroundings peculiarities and the landlord and tenant relationships.

The outcome of this study could strengthen policies in creating design standards for construction of housing for renters; this is step towards achieving Sustainable Development Goal (SDG) 11, creating an inclusive communities.

The purpose of this study was to investigate the views of librarians in Iran academic libraries about the extent of their familiarity, application and knowledge of the cloud computing in libraries.

This was a survey research. The statistical population of research consisted of librarians working in five universities in northeastern Iran. The sample (83 librarian) selected by using random sampling method.

The findings showed that in 2019 librarians familiar with cloud computing was low, but their use of cloud computing services was moderate. Also the findings showed that the item of providing enough computers in the library had the lowest effect on promoting the use of cloud computing and the items. Cloud computing training for librarians and users and broadband Internet were best strategies offered by librarians to promote the use of cloud computing.

Cloud computing has received less attention from librarians and researchers. However, based on the results of the present study, the broader use of cloud computing in libraries requires specialized and trained staff. Librarians need to broaden their knowledge in this technology.