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In the face of pressing global challenges, the role of educational institutions in fostering responsible management practices has never been more crucial. Drawing on the preceding chapters, this concluding contribution explores the nexus of innovation and social impact within the realm of responsible management education (RME), offering a synthesis of perspectives and strategies for driving positive change at micro-, meso-, and macro level. The authors argue that the frequent inertia of higher education institutions must be overcome with urgent action in reshaping curricula, teaching methodologies, and institutional policies to foster sustainable development and effect positive social impact. The chapter emphasizes the role of innovation in education and the development and diffusion of responsible business practices as a means to catalyze systemic change.