Anna Visvizi, Miltiadis D. Lytras, Ernesto Damiani and Hassan Mathkour
T.C. Venkateswarulu, Asra Tasneem Shaik, Druthi Sri Meduri, Vajiha Vajiha, Kalyani Dhusia and Abraham Peele
Mucorales has been described to be widely distributed during the most recent COVID-19 pandemic, with a greater frequency of disease in India, particularly among those with immune…
Abstract
Purpose
Mucorales has been described to be widely distributed during the most recent COVID-19 pandemic, with a greater frequency of disease in India, particularly among those with immune deficiencies. This study aims to use computational tools to develop a vaccine.
Design/methodology/approach
The authors investigated at Mucorales proteins that had previously been associated to virulence factors. Recent research suggests that a vaccine based on high-level cytotoxic T lymphocyte (CTL), helper T lymphocyte (HTL) and B-cell lymphocyte (BCL) epitopes from diverse proteins might be developed. Furthermore, the vaccine assembly contains the targeted epitopes as well as PADRE peptides to induce an immune response. Computational approaches were used to analyze the immunological parameters used to build the suggested vaccine and validate its TLR-3 binding.
Findings
These studies show that the vaccination is capable of triggering a particular immune response. The authors offer a technique for developing and evaluating candidate vaccines using computational tools. To the best of their knowledge, this is the first immunoinformatic research of a prospective mucormycosis vaccine.
Originality/value
During this audit, a successful attempt was made to create a subunit MEV against black fungus. In the current study, MEV has been proposed as a suitable neutralizer candidate since it is immunogenic, secure, stable and interacts with human receptors. A stream study, on the other hand, is produced via a mixed vaccinosis approach. Following that, vaccinologists may perform more exploratory testing to evaluate whether the vaccine is effective.
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Ashish Dwivedi, Ajay Jha, Dhirendra Prajapati, Nenavath Sreenu and Saurabh Pratap
Due to unceasing declination in environment, sustainable agro-food supply chains have become a topic of concern to business, government organizations and customers. The purpose of…
Abstract
Purpose
Due to unceasing declination in environment, sustainable agro-food supply chains have become a topic of concern to business, government organizations and customers. The purpose of this study is to examine a problem associated with sustainable network design in context of Indian agro-food grain supply chain.
Design/methodology/approach
A mixed integer nonlinear programming (MINLP) model is suggested to apprehend the major complications related with two-echelon food grain supply chain along with sustainability aspects (carbon emissions). Genetic algorithm (GA) and quantum-based genetic algorithm (Q-GA), two meta-heuristic algorithms and LINGO 18 (traditional approach) are employed to establish the vehicle allocation and selection of orders set.
Findings
The model minimizes the total transportation cost and carbon emission tax in gathering food grains from farmers to the hubs and later to the selected demand points (warehouses). The simulated data are adopted to test and validate the suggested model. The computational experiments concede that the performance of LINGO is superior than meta-heuristic algorithms (GA and Q-GA) in terms of solution obtained, but there is trade-off with respect to computational time.
Research limitations/implications
In literature, inadequate study has been perceived on defining environmental sustainable issues connected with agro-food supply chain from farmer to final distribution centers. A MINLP model has been formulated as practical scenario for central part of India that captures all the major complexities to make the system more efficient. This study is regulated to agro-food Indian industries.
Originality/value
The suggested network design problem is an innovative approach to design distribution systems from farmers to the hubs and later to the selected warehouses. This study considerably assists the organizations to design their distribution network more efficiently.
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Zhe Chen, Apurbo Sarkar, Xiaojing Li and Xianli Xia
Based on the survey data of 650 kiwi growers from Shaanxi and Sichuan provinces, this paper used multiple endogenous transformation regression models to explore the effect of the…
Abstract
Purpose
Based on the survey data of 650 kiwi growers from Shaanxi and Sichuan provinces, this paper used multiple endogenous transformation regression models to explore the effect of the joint adoption of green production technology on farmer’s welfare. The purpose of the study is to analyze the influence of green production technology on the yield, household income and socioeconomic characteristics of Kiwi fruit growers.
Design/methodology/approach
In the context of the study, multiple endogenous transformation model (MESR) are adopted, but self-actualization tactics were adopted to deal with the instrumental variables. The empirical data has been collected via a combined hierarchical sampling and random sampling, whereas a well-structured Likert scale questionnaire was adopted as well. The empirical data has been processed with the help of STATA 15.1 version.
Findings
The study found a positive impact of adopting green production technology. Moreover, the joint adoption of green production technology by kiwi growers has significantly increased the yield, economic values of Kiwi and household income of kiwi farmers. The households with higher asset value, better land quality, weaker credit constraints, more technical training and stronger government promotion and support from local governments are the most likely to adopt pest control technology and soil management technology jointly.
Originality/value
The prime innovation of the paper is to measure the impact of technology combination adoption on farmer’s welfare is evaluated, rather than the impact of single sub technology on farmer’s’ welfare.
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Inma Rodríguez-Ardura and Antoni Meseguer-Artola
Mobile Facebook (m-Facebook) creates many business opportunities for brands and firms while increasingly drawing interest in scientific literature. However, research is scarce on…
Abstract
Purpose
Mobile Facebook (m-Facebook) creates many business opportunities for brands and firms while increasingly drawing interest in scientific literature. However, research is scarce on the immersive experiences prompted by m-Facebook, and how these experiences facilitate users’ engagement, their positive attitude towards Facebook and their continued use of it. The paper aims to discuss these issues.
Design/methodology/approach
This paper theoretically and empirically analyses m-Facebook users’ immersive experiences, along with their affective and behavioural effects.
Findings
The results reveal the important role of imagery, presence and flow in the context of m-Facebook; the interplay between these three immersive phenomena; and the influence the user’s optimum stimulation level has on them.
Originality/value
The investigation offers a foundation for understanding users’ immersive experiences on m-Facebook, and informs practitioners who aim to enhance users’ engagement with, attitude towards, and continued use of m-Facebook content.
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Eline Punt, Jochen Monstadt, Sybille Frank and Patrick Witte
Cyber resilience has emerged as an approach for seaports to deal with cyberattacks; it emphasizes ports’ ability to prepare for an attack and to keep operating and recover…
Abstract
Purpose
Cyber resilience has emerged as an approach for seaports to deal with cyberattacks; it emphasizes ports’ ability to prepare for an attack and to keep operating and recover quickly. However, little research has been undertaken on the challenges of governing cyber risks in seaports. This study aims to address this gap.
Design/methodology/approach
Governing cyber resilience is shaped by distributed responsibilities, uncertainties and ambiguities. The authors use this conceptualization to explore the governance of cyber risks in seaports, taking the Port of Rotterdam as a case study and analyzing semistructured interviews with stakeholders, participatory observation and policy documents and legislation.
Findings
The authors found that many strategies for governing cyber risks remain dedicated to protecting computer systems against cyberattacks. Nevertheless, port stakeholders have also developed strategies in anticipation of disruptions. However, these strategies appear informal and uncoordinated due to a lack of information exchange, insufficient knowledge regarding cyber risks and disagreement about how to make the Port of Rotterdam cyber resilient. What mainly hampers the cyber resilience of the port is the lack of a comprehensive regulatory framework and economic incentives. The authors conclude that resilience is merely an ideal at the Port of Rotterdam, meaning related governance strategies remain incremental and await institutionalization.
Originality/value
This paper offers insights into the cyber resilience of critical socio-technical systems, which have been underexposed in cyber resilience debates, but, when exploited, can manifest in large-scale disruptions.