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In the developing field of nano-materials synthesis, copper oxide nanoparticles (NPs) are deemed to be one of the most significant transition metal oxides because of their intriguing characteristics. Its synthesis employing green chemistry principles has become a key source for next-generation antibiotics attributed to its features such as environmental friendliness, ease of use and affordability. Because they are more environmentally benign, plants have been employed to create metallic NPs. These plant extracts serve as capping, stabilising or hydrolytic agents and enable a regulated synthesis as well.

Organic chemical solvents are harmful and entail intense conditions during nanoparticle synthesis. The copper oxide NPs (CuO-NPs) synthesised by employing the green chemistry principle showed potential antitumor properties. Green synthesised CuO-NPs are regarded to be a strong contender for applications in the pharmacological, biomedical and environmental fields.

The aim of this study is to evaluate the anticancer potential of CuO-NPs plant extracts to isolate and characterise the active anticancer principles as well as to yield more effective, affordable, and safer cancer therapies.

This review article highlights the copper oxide nanoparticle's biomedical applications such as anticancer, antimicrobial, dental and drug delivery properties, future research perspectives and direction are also discussed.

In response to the growing demand for a polymer with improved chemical and thermal stability in the construction sector, this study aims to thoroughly explore the characteristics of silver nanoparticles (AgNP) and their various concentrations. The primary goal is to determine the effect of these nanoparticles on the chemical and thermal stability of unsaturated polyester (UPE) resin doped with dimethyl-para-toluidine (DMPT) when exposed to high temperatures.

Silver nanoparticles were first synthesized from the chemical reaction between silver nitrate and trisodium citrate before its addition to the resin. The nanocomposites were thoroughly examined using advanced analytical methods such as Fourier transform (FTIR), Raman spectroscopy and scanning electron microscope to determine chemical stability. Thermal stability tests were carried out using thermogravimetric analysis, differential thermal analysis and derivative thermogravimetry methods; viscosity and peak exotherm were also examined.

The data shows that increasing nanoparticle concentration improves resin chemical stability, reduces peak exotherm duration and increases viscosity. Clearly, only 1.5% AgNP concentration outperformed neat UPE resin, while 0.5% and 1% AgNP concentrations fall short in terms of thermal stability.

The enhanced resin highlights the subtle influence of nanoparticle addition, which has a greater impact on the chemical structure of the composite rather than its thermal properties.

The purpose of this paper is to establish a chair-side design and production method for a tooth-supported fixed implant guide and to evaluate its accuracy.

Three-dimensional (3D) data of the alveolar ridge, adjacent teeth and antagonistic teeth were acquired from models of the edentulous area of 30 patients. The implant guides were then constructed using self-developed computer-aided design software and chair-side fused deposition modelling 3D-printing and positioned on a dental model. A model scanner was used to acquire 3D data of the positioned implant guides, and the overall error was then evaluated.

The overall error was 0.599 ± 0.146 mm (n = 30). One-way ANOVA revealed no statistical differences among the 30 implant guides. The gap between the occlusal surface of the teeth covering and the tissue surface of the implant guide was measured. The maximum gap after positioning of the implant guide was 0.341 mm (mean, 0.179 ± 0.019 mm). The implanted axes of the printed implant guide and designed guide were compared in terms of overall, lateral and angular error, which were 0.104 ± 0.004 mm, 0.097 ± 0.003 mm, and 2.053° ± 0.017°, respectively.

The results of this study demonstrated that the accuracy of a new chair-side tooth-supported fixed implant guide can satisfy clinical requirements.