Tancredi Pascucci, Brizeida Hernández Sánchez and José Carlos Sánchez García
Work-family conflict is an important topic which had an evolution, starting from a static definition, where work and family domains were divided, to a more dynamic and complex…
Abstract
Purpose
Work-family conflict is an important topic which had an evolution, starting from a static definition, where work and family domains were divided, to a more dynamic and complex balance. COVID-19 has influenced society and created a significant distress among families and working activity, and this topic has been characterised by a major interest, considering some old definitions where this balance was considered problematic but not as an enriching opportunity.
Design/methodology/approach
The authors used SCOPUS to find all records mentioning work-family conflict, by considering book, article and review, excluding conference paper and considering only records written in English language. After a duplicated and not pertinent record removal, the authors obtained a number of 675 records. The authors considered 437 records from SCOPUS to create a cluster map.
Findings
Using SCOPUS and VOSviewer the authors have clustered 5 different areas, which are regrouped in next clusters considering keywords with most co-occurrence and significancy: Work-life balance and burnout gender cluster job stress and performance social and family support job satisfaction.
Research limitations/implications
Cluster map is origined only by SCOPUS database.
Originality/value
This work aims to find a state of art about this topic, creating hypothesis where this problem has been exacerbated by 2020 due to important society modifications created by COVID-19, where recent evolution of work-family balance has been complicated by papers which come back to consider this balance as problematic.
Details
Keywords
Amina Tawfik, Samia Shouman, Reda Tabashy, Mervat Omran and Mohamed Gad El-Mola
This scientific article aims to evaluate the efficacy of the drug Doxorubicin for treating hepatocellular carcinoma (HCC) in Egypt. The study analyzes data from patients referred…
Abstract
Purpose
This scientific article aims to evaluate the efficacy of the drug Doxorubicin for treating hepatocellular carcinoma (HCC) in Egypt. The study analyzes data from patients referred to a multi-disciplinary consultation at the National Cancer Institute, Cairo University. The study includes 40 intermediate-stage HCC patients who underwent treatment with either Doxorubicin-Lipiodol or Doxorubicin-loaded drug-eluting beads-trans-arterial chemoembolization (DEB-TACE).
Design/methodology/approach
Patients referred to a multi-disciplinary consultation at the National Cancer Institute, Cairo University with a possible diagnosis of HCC in the intermediate stage were eligible for the study.
Findings
The study finds that the plasma peak concentration of Doxorubicin is significantly higher in patients treated with Lipiodol compared to those treated with DEB-TACE. The median plasma peak concentration of patients treated with Lipiodol was significantly higher 424 (202.5–731) than the peak level of patients treated with beads 84.95 (26.6–156.5) with p-value = 0.036. However, there is no significant difference in other pharmacokinetic parameters between the two treatment groups. The research article also investigates the genetic polymorphisms in HCC patients treated with Doxorubicin-Lipiodol and Doxorubicin-loaded DEB-TACE. It identifies a significant association between the ABCB1 gene (C3435T) and the concentration of Doxorubicin in plasma. Patients with the CCand computed tomography (CT) genotypes of ABCB1 have higher concentrations of Doxorubicin compared to those with the TT genotype. Furthermore, the study examines the progression-free survival rates and tumour response in the two treatment groups. It demonstrates that DEB-TACE patients have a higher progression-free survival rate compared to cTACE patients. DEB-TACE also leads to better tumour regression.
Originality/value
The current study helps to increase the understanding of the genetic factors that may contribute to HCC susceptibility in the Egyptian population. However, it is essential to consider that genetic polymorphism is just one aspect of HCC risk, and other factors such as environment, lifestyle and viral infections also play crucial roles. Further research is needed to elucidate the complex interactions between genetic and environmental factors in HCC development among Egyptians.
Details
Keywords
The belt and road initiative (BRI) emanates from China and seeks to connect Europe, Asia and Africa through transport and telecommunications infrastructure. Despite the importance…
Abstract
Purpose
The belt and road initiative (BRI) emanates from China and seeks to connect Europe, Asia and Africa through transport and telecommunications infrastructure. Despite the importance of Africa in the BRI network, very little research has been done on the BRI in Africa, and even less of this emanates from Africa itself. In particular, considering that the BRI investments in Africa are largely transport related, there is almost no research covering the area of logistics, which should be greatly affected by the infrastructure investments. This paper sought to establish the current state of logistics research related to the BRI in Africa.
Design/methodology/approach
A bibliometric analysis was conducted on documents extracted from the SCOPUS database.
Findings
The findings indicate that there is a lack of research in critical areas such as environmental, social and economic impact of BRI transport investments, governance, logistics performance and international cooperation. In particular, there is a massive gap in local knowledge regarding the BRI.
Research limitations/implications
The study is limited to published research indexed in the SCOPUS database. Future research directions include empirical studies into BRI project initiation investigation, economic and environmental impacts, governance structures and policy intervention requirements and macro-level logistics impacts.
Practical implications
The study emphasises the importance publishing all the relevant information regarding BRI related projects in Africa to create transparency.
Originality/value
The study investigates the current research on the effect of China's BRI on transport and logistics in Africa through a bibliometric analysis. The investigation reveals that while there are huge investments in infrastructure, the actual effect on logistics of participating countries in Africa has not been interrogated.