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This study compares the fatigue performance and biocompatibility of as-built and chemically etched Ti-6Al-4V alloys in TPMS-gyroid and stochastic structures fabricated via Powder Bed Fusion Laser Beam (PBF-LB). This study aims to understand how complex lattice structures and post-manufacturing treatment, particularly chemical etching, affect the mechanical properties, surface morphology, fatigue resistance and biocompatibility of these metamaterials for biomedical applications.

Selective Laser Melting (SLM) technology was used to fabricate TPMS-gyroid and Voronoi stochastic designs with three different relative densities (0.2, 0.3 and 0.4) in Ti-6Al-4V ELI alloy. The as-built samples underwent a chemical etching process to enhance surface quality. Mechanical characterization included static compression and dynamic fatigue testing, complemented by scanning electron microscopy (SEM) for surface and failure analysis. The biocompatibility of the samples was assessed through in-vitro cell viability assays using the Alamar Blue assay and cell proliferation studies.

Chemical etching significantly improves the surface morphology, mechanical properties and fatigue resistance of both TPMS-gyroid and stochastic structures. Gyroid structures demonstrated superior mechanical performance and fatigue resistance compared to stochastic structures, with etching providing more pronounced benefits in these aspects. In-vitro biocompatibility tests showed high cytocompatibility for both as-built and etched samples, with etched samples exhibiting notably improved cell viability. The study also highlights the importance of design and post-processing in optimizing the performance of Ti64 components for biomedical applications.

The comparative analysis between as-built and etched conditions, alongside considering different lattice designs, provides valuable information for developing advanced biomedical implants. The demonstration of enhanced fatigue resistance and biocompatibility through etching adds significant value to the field of additive manufacturing, suggesting new avenues for designing and post-processing implantable devices.

Productivity is often cited as a key barrier to the adoption of metal laser-based powder bed fusion (ML-PBF) technology for mass production. Newer generations of this technology work to overcome this by introducing more lasers or dramatically different processing techniques. Current generation ML-PBF machines are typically not capable of taking on additional hardware to maximise productivity due to inherent design limitations. Thus, any increases to be found in this generation of machines need to be implemented through design or adjusting how the machine currently processes the material. The purpose of this paper is to identify the most beneficial existing methodologies for the optimisation of productivity in existing ML-PBF equipment so that current users have a framework upon which they can improve their processes.

The review method used here is the preferred reporting items for systematic review and meta-analysis (PRISMA). This is complemented by using an artificial intelligence-assisted literature review tool known as Elicit. Scopus, WEEE, Web of Science and Semantic Scholar databases were searched for articles using specific keywords and Boolean operators.

The PRIMSA and Elicit processes resulted in 51 papers that met the criteria. Of these, 24 indicated that by using a design of experiment approach, processing parameters could be created that would increase productivity. The other themes identified include scan strategy (11), surface alteration (11), changing of layer heights (17), artificial neural networks (3) and altering of the material (5). Due to the nature of the studies, quantifying the effect of these themes on productivity was not always possible. However, studies citing altering layer heights and processing parameters indicated the greatest quantifiable increase in productivity with values between 10% and 252% cited. The literature, though not always explicit, depicts several avenues for the improvement of productivity for current-generation ML-PBF machines.

This systematic literature review provides trends and themes that aim to influence and support future research directions for maximising the productivity of the ML-PBF machines.