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The paper aims to interpret sustainable regional development (SRD) as an exchange ecosystem in which stakeholders provide reciprocal access to resources, benefiting both individual and systemic levels. This paper suggests that knowledge, as a shared and value-transcribed critical resource, nourishes a community’s motivational system (CMS), orienting it toward SRD. This inherently raises questions regarding the nature of social business models (SBM) that can best support community’s motivational system, as well as their sustainable regional development derivatives.

This paper employs the Fuzzy Expert System (FES) to analyze companies participating in the three most representative Italian consortia, aiming to empirically address the knowledge gap regarding the influence of social business model on sustainable regional development.

Applying our theoretical framework to Agro-food Protection Consortia – a specific type of hybrid social, regional value-oriented business organization – this paper demonstrates that knowledge sharing along environmental, social and economic dimensions enhances sustainable regional development. Using the IF (condition) → THEN (action) logic of fuzzy method, the study identified knowledge exchange as a key condition motivating actors to contribute to sustainable regional development. This dynamic approach enables better alignment between stakeholders and regional goals.

This paper presents practicable participatory strategic guidelines that balance informal and formal governance mechanisms with the catalytic and enhancing connection of strategic business initiatives for Sustainable Regional Development.

This research delves into the realm of Business Model Innovation (BMI), integrating it with the human-centric, sustainable, and resilient principles of Industry 5.0, proposing a new theoretical framework.

An abductive approach has been chosen to expand existing knowledge developing new ideas based on emerging phenomena. Data were gathered via semi-structured interviews with directors, managers and curators of public institutions in Italy, Switzerland, Germany and Spain encompassing Galleries, Libraries, Archives, and Museums (GLAM). These data were subsequently subjected to thematic analysis.

The findings indicate that the main enablers for Business Model Innovation (BMI) in combination with Industry 5.0 encompassed stakeholder, customer and organizational engagement, collaborative environment, knowledge and innovation management, and sustainability. These drivers were effectively leveraged through three pivotal facilitators-inhibitors: technology, resources, and leadership.

The principal constraints are rooted in the narrow contextual focus and the limited participants number. However, upcoming research efforts may broaden the horizons of this multifaceted and extensive investigation.

This study is groundbreaking as it fills a significant gap in the existing literature by integrating Business Model Innovation (BMI) with the Industry 5.0 paradigm, a novel approach that has not been explored previously. Additionally, the inclusion of GLAM institutions in this research adds a unique dimension, as they have been largely overlooked in both research domains.