Effects of daily aspirin on cancer incidence, mortality, and non-vascular death

Citation

(2012), "Effects of daily aspirin on cancer incidence, mortality, and non-vascular death", Clinical Governance: An International Journal, Vol. 17 No. 3. https://doi.org/10.1108/cgij.2012.24817caa.007

Effects of daily aspirin on cancer incidence, mortality, and non-vascular death

Effects of daily aspirin on cancer incidence, mortality, and non-vascular death

Article Type: Reviews of effectiveness From: Clinical Governance: An International Journal, Volume 17, Issue 3

Rothwell, P.M., Price, J.F., Fowkes, F.G., Zanchetti, A., Roncaglioni, M.C., Tognoni, G., Lee, R., Belch, J.F., Wilson, M., Mehta, Z., Meade, T.W.,Short-term effects of daily aspirin on cancer incidence, mortality, and non-vascular death: analysis of the time course of risks and benefits in 51 randomised controlled trials,Lancet,2012,Vol. 344,doi:10.1016/S0140-6736(11)61720-0

This meta-analysis used mainly individual patient data on people treated with low-dose daily aspirin for primary prevention of vascular events. The authors found a short-term reduction in cancer incidence and mortality and a decrease in major extracranial bleeds with extended use of aspirin. Despite being based on a subset of included trials, the findings appear reliable.