Diagnostic testing for celiac disease among patients with abdominal symptoms

Citation

(2011), "Diagnostic testing for celiac disease among patients with abdominal symptoms", Clinical Governance: An International Journal, Vol. 16 No. 2. https://doi.org/10.1108/cgij.2011.24816bae.013

Diagnostic testing for celiac disease among patients with abdominal symptoms

Article Type: Reviews of effectiveness From: Clinical Governance: An International Journal, Volume 16, Issue 2

van der Windt, D.A., Jellema, P., Mulder, C.J., Frank Kneepkens, C.M. and van der Horst, H.E.,Diagnostic testing for celiac disease among patients with abdominal symptoms: a systematic review,JAMA,2010,Vol. 303,pp. 1738-1746

This review assessed diagnostic accuracy of tests for coeliac disease in adults who presented with abdominal symptoms in primary care or similar settings and concluded that Immunoglobulin-A anti-tissue transglutaminase antibodies and Immunoglobulin-A anti-endomysial antibodies showed good diagnostic performance. The authors’ conclusions appear to reflect the evidence, but there may have been some bias in the included studies and review process.