RETRACTED: Modern chromatographic method for estimating Loratadine and affections on healthcare
International Journal of Human Rights in Healthcare
ISSN: 2056-4902
Article publication date: 11 October 2021
Issue publication date: 29 August 2024
Retraction statement
The publishers of the International Journal of Human Rights in Healthcare wish to retract the article Al-Salman, H.N.K., Qasim, Q.A., Fayadh, R.H. and Hussein, H.H. (2021), “Modern chromatographic method for estimating Loratadine and affections on healthcare”, International Journal of Human Rights in Healthcare, Vol. ahead-of-print No. ahead-of-print. https://doi.org/10.1108/IJHRH-08-2021-0154.
An internal investigation into a series of submissions has uncovered evidence that the peer review process was compromised. As a result of these concerns, the findings of the article cannot be relied upon. This decision has been taken in accordance with Emerald’s publishing ethics and the COPE guidelines on retractions.
Despite numerous attempts to contact the authors, the journal has received no response; the response of the authors would be gratefully received.
The publishers of the journal sincerely apologize to the readers.
The retracted article is available at: https://doi.org/10.1108/IJHRH-08-2021-0154.
Abstract
Purpose
The purpose of this study is to establish Loratadine [LRD] quantification in purified and capsule formulations using a precise and specific Reversal Phase with a very high-performance liquid Chromatographic [RP-HPLC] technique. The approach was evaluated in agreement with the principles of the International Conference on Harmonization [ICH]. Arcus EP-C18 Ion Pac column, 5 m, 4.6 mm, 250 mm, mobile phase Methanol: Acetonitrile (60:40) v/v. Dibasic potassium phosphate buffer, pH 7.2, flow rate 1.0 ml/min.
Design/methodology/approach
The HPLC system used a 340 nm UV detector for testing. A 10-min run time was used for the analysis. At concentrations ranging from 2 to 10 g/ml, the technique was linear (R2 = 0.9998), exact (intra-day and inter-day relative standard deviation [RSD] values 1.0%), accurate (range recovery = 96%–102%), exclusive and strong.
Findings
The detecting and quantitation limits were 0.92 g/ml and 2.15 g/ml, respectively.
Originality/value
The findings demonstrated that the proposed method could accurately determine LRD in bulk and pill dose formats quickly and accurately.
Keywords
Acknowledgements
The authors are thankful to the instructors of the College of Pharmacy's Pharmaceutical Chemistry Branch for their support in producing this publication.Authors’ contributions: this study was carried out independently at the laboratories of the University of Basrah's College of Pharmacy. This study was done over the course of three months with serious and constant effort, yielding outstanding results in terms of identifying a simple and sensitive approach for estimating the LDR.
Citation
Al-Salman, H.N.K., Qasim, Q.A., Fayadh, R.H. and Hussein, H.H. (2024), "RETRACTED: Modern chromatographic method for estimating Loratadine and affections on healthcare", International Journal of Human Rights in Healthcare, Vol. 17 No. 4, pp. 507-520. https://doi.org/10.1108/IJHRH-08-2021-0154
Publisher
:Emerald Publishing Limited
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